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Published on: August 8, 2022
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Hypertrophic Cardiomyopathy and Pregnancy
Amha Weldehana1, Beeletsega Yeneneh2, Samrawit Zewde3
1From the Department of Cardiology, Westchester Medical Center, Valhalla, NY.
Cardiology in Review
|June 20, 2025
Summary
Hypertrophic cardiomyopathy (HCM) in pregnancy is increasingly common. While often well-tolerated, this review examines diagnosis, risks, and management for expectant mothers with HCM.
Area of Science:
- Cardiology
- Genetics
- Obstetrics
Background:
- Hypertrophic cardiomyopathy (HCM) is an inherited condition affecting the heart muscle.
- Increased screening leads to more women of reproductive age with HCM becoming pregnant.
- Limited evidence exists on managing HCM during pregnancy.
Purpose of the Study:
- To review the epidemiology of HCM in pregnancy.
- To discuss clinical presentation and diagnostic challenges.
- To outline management strategies for pregnant patients with HCM.
Main Methods:
- Literature review of observational studies.
- Analysis of clinical evidence on HCM and pregnancy.
- Synthesis of data on diagnosis, risk stratification, and management.
Main Results:
- HCM is generally well-tolerated during pregnancy for many women.
- Normal pregnancy and delivery outcomes are frequently observed.
- Potential complications necessitate pre-pregnancy intervention considerations.
Conclusions:
- Pregnancy in women with HCM requires careful consideration of potential risks.
- Early diagnosis and risk stratification are crucial.
- Management strategies should be individualized, with potential need for advanced interventions.
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