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Investigating Microplastic Presence in Eye Drops Using Micro-Fourier Transform Infrared Spectroscopy.

Geraldine Yang1, Jerome Ozkan1, Minas Coroneo1,2

  • 1University of New South Wales, Sydney, Australia ; and.

Cornea
|June 20, 2025
PubMed
Summary
This summary is machine-generated.

Microplastics (MPs) were found in commercial eye drops, raising health concerns. Further research is needed to identify sources and assess risks from these plastic particles in ocular medications.

Keywords:
eye dropsmicro-Fourier Transform Infrared spectroscopymicroplasticsocular medications

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Area of Science:

  • Ophthalmology
  • Environmental Health
  • Materials Science

Background:

  • Microplastics (MPs) are pervasive environmental contaminants with potential health implications.
  • The ocular surface is a potential route for MP exposure through contaminated medications.
  • Previous studies suggest MPs may cause ocular surface inflammation and damage.

Purpose of the Study:

  • To investigate the presence of microplastics (MPs) in commercially available eye drops.
  • To assess the potential for MP contamination in topical ocular medications.
  • To understand the pathways of MPs into ocular and systemic tissues.

Main Methods:

  • Analysis of 60 samples from 20 brands of commercial eye drops.
  • Identification of particles ≥20 μm using micro-Fourier Transform Infrared Spectroscopy.
  • Confirmation of MP identity against polymer and chemical databases.

Main Results:

  • Four microplastics (MPs) were identified in two eye drop samples.
  • Detected MPs included poly(1-dodecene) and poly(1-octene) films.
  • Additional non-MP particles, such as chemical catalysts, were also found.

Conclusions:

  • Commercial eye drops can contain microplastics (MPs) ≥20 μm.
  • The origin of MPs in eye drops (packaging or ingredients) requires further investigation.
  • Advanced techniques like micro-Raman spectroscopy are recommended for definitive MP analysis.