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Updated: Sep 18, 2025

High Frequency Ultrasound for the Analysis of Fetal and Placental Development In Vivo
Published on: November 8, 2018
2nd trimester ultrasound (anomaly)
Ana Carocha1, Maria Vicente2, Joana Bernardeco1
1Fetal Medicine and Surgery Unit, Unidade Local de Saúde São José, Lisboa, Portugal.
Abstract:
The second-trimester ultrasound is a crucial tool in prenatal care, typically conducted between 18 and 24 weeks of gestation to evaluate fetal anatomy, growth, and mid-trimester screening. This article provides a comprehensive overview of the best practices and guidelines for performing this examination, with a focus on detecting fetal anomalies. The ultrasound assesses key structures and evaluates fetal growth by measuring biometric parameters, which are essential for estimating fetal weight. Additionally, the article discusses the importance of placental evaluation, amniotic fluid levels measurement, and the risk of preterm birth through cervical length measurements. Factors that can affect the accuracy of the scan, such as the skill of the operator, the quality of the equipment, and maternal conditions such as obesity, are discussed. The article also addresses the limitations of the procedure, including variability in detection. Despite these challenges, the second-trimester ultrasound remains a valuable screening and diagnostic tool, providing essential information for managing pregnancies, especially in high-risk cases. Future directions include improving imaging technology, integrating artificial intelligence for anomaly detection, and standardizing ultrasound protocols to enhance diagnostic accuracy and ensure consistent prenatal care.
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