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Updated: Sep 18, 2025

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High Frequency Ultrasound for the Analysis of Fetal and Placental Development In Vivo
Published on: November 8, 2018
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2nd trimester ultrasound (anomaly).
Ana Carocha1, Maria Vicente2, Joana Bernardeco1
1Fetal Medicine and Surgery Unit, Unidade Local de Saúde São José, Lisboa, Portugal.
Summary
The second-trimester ultrasound, performed between 18-24 weeks, is vital for assessing fetal health and detecting anomalies. Best practices ensure accurate prenatal screening and management, especially for high-risk pregnancies.
Area of Science:
- Obstetrics and Gynecology
- Medical Imaging
- Fetal Medicine
Background:
- The second-trimester ultrasound is a cornerstone of prenatal care.
- It is typically performed between 18 and 24 weeks of gestation.
- This examination is critical for evaluating fetal anatomy, growth, and screening for mid-trimester anomalies.
Purpose of the Study:
- To provide a comprehensive overview of best practices and guidelines for second-trimester ultrasound.
- To emphasize the role of this scan in detecting fetal anomalies.
- To discuss factors influencing scan accuracy and limitations.
Main Methods:
- Review of established protocols for second-trimester ultrasound examinations.
- Assessment of key fetal structures and biometric parameters for growth evaluation.
- Evaluation of placental health, amniotic fluid levels, and cervical length for preterm birth risk.
Main Results:
- The ultrasound assesses fetal anatomy, estimates fetal weight via biometric measurements, and evaluates placental and amniotic fluid status.
- Cervical length measurement aids in assessing preterm birth risk.
- Operator skill, equipment quality, and maternal factors like obesity can impact scan accuracy.
Conclusions:
- The second-trimester ultrasound is an indispensable tool for pregnancy management, particularly in high-risk cases.
- Despite limitations in detection variability, it provides crucial screening and diagnostic information.
- Future advancements aim to enhance accuracy through improved technology, AI integration, and standardized protocols.
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