Two sides of a co(i)ndensate
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Updated: Sep 18, 2025

Author Spotlight: Developing Synthetic Cells from Programmable Amphiphilic DNA Nanostructures
Published on: May 31, 2024
Emre Pekbilir1, Dorothee Dormann2
1Johannes Gutenberg University (JGU) Mainz, Faculty of Biology, Institute of Molecular Physiology, Mainz, Germany; International PhD Programme (IPP) of Institute of Molecular Biology (IMB), Mainz, Germany.
Abstract:
In the June 5th issue of Molecular Cell, Das et al.1 quantified the stability of condensates and fibrils formed from the prion-like low complexity region of hnRNPA1. They demonstrate that condensate interiors function as sinks and suppress fibril growth by slowing protein efflux, illuminating the interplay between condensation and fibril formation.
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