Related Experiment Video
Updated: Sep 18, 2025
Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
Published on: October 20, 2017
A Novel Approach for Cerebral Embolic Protection With Single-Artery Access in TAVR
Isaac George1, Maximilian Reisinger2, Mateusz Kachel3
1Division of Cardiac, Thoracic, and Vascular Surgery, New York-Presbyterian Hospital, Columbia University Irving Medical Center, New York, New York, USA; Structural Heart and Valve Center, New York-Presbyterian Hospital, Columbia University Irving Medical Center, New York, New York, USA.
Background:
Cerebral embolic protection devices (CEPDs) have been developed to decrease embolic brain injury and stroke during transcatheter aortic valve replacement (TAVR). Simplifying vascular access for a CEPD may increase procedural efficiency and safety FIRST-IN-HUMAN/EARLY REPORTS SUMMARY: This is the first published report of the use of the novel EnCompass F2 filter, which consists of a cylindrical nitinol frame and electrospun filter. Complete cerebral embolic protection during TAVR is possible through single femoral arterial access.
Discussion:
Cerebral protection was feasible and safe without device-related complications, clinical stroke, or other neurologic events. Postprocedural diffusion-weighted magnetic resonance imaging revealed only 1 very small, clinically insignificant new brain lesion.
Novelty:
This presents the first successful use of a CEPD in TAVR through access by a single femoral artery.
Take-Home Message:
The use of the novel EnCompass F2 filter was feasible to provide complete cerebral embolic protection in TAVR using a single access.
