Early experience with the Drivewire 24: a newly FDA-approved steerable microwire.

Area of Science:

• Neurosurgery
• Interventional Neurology
• Medical Devices

Background:

• The Drivewire 24 (DW24) is a novel 0.024 inch steerable guidewire with FDA clearance.
• Its deflectable tip enables precise intravascular steering for catheter navigation.

Purpose of the Study:

• To evaluate the initial clinical experience and performance of the DW24 guidewire in neurointerventional procedures.
• To assess its safety, efficacy, and operator feedback.

Main Methods:

• Retrospective review of 27 neurointerventional procedures using the DW24 from October 2024 to April 2025.
• Analysis of indications, procedural details, DW24 performance, complications, and operator feedback.

Main Results:

• High technical success rate of 92.6% across various indications including aneurysms and stroke.
• Demonstrated effective navigation in challenging cerebrovasculature, including cases where conventional wires failed.
• Facilitated catheter delivery for Pipeline Embolization Device (PED) placement and post-processing without wire removal.

Conclusions:

• The DW24 guidewire shows high technical success and a favorable safety profile with no device-related complications.
• Its steerability and versatility are beneficial for complex neurovascular interventions.
• Further research in larger cohorts and diverse clinical scenarios is warranted.