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P-Selectin(g) a diagnostic biomarker in heparin-induced thrombocytopenia

James V Michael1

  • 1The Cardeza Foundation for Hematologic Research, Center for Hemostasis, Thrombosis and Vascular Biology, Department of Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

Journal of Thrombosis and Haemostasis : JTH
|June 21, 2025
PubMed
Abstract

No abstract available in PubMed .

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Cell adhesion is  an essential aspect of multicellularity. While stable cell interactions usually occur between cells of the same type, transient cell interactions occur between cells of different tissue types, such as between neutrophils and endothelial cells. Selectins are one class of cell adhesion molecules (CAMs) that bind carbohydrate ligands to form transient cell adhesion. They are rod-like proteins with a long extracellular part of variable length ending with the lectin domain,...
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