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Endocrine Disruptors and Attention Deficit Hyperactivity Disorder: A Systematic Review
Marta Lopez-Garcia1, Manuel Martinez-Bebia1, Alejandro Lopez-Moro2
1Department of Food Technology, Nutrition and Food Science, University of Murcia, Murcia, Spain.
Exposure to endocrine-disrupting chemicals like bisphenol A (BPA) and polychlorinated biphenyls (PCBs) may increase the risk of attention deficit hyperactivity disorder (ADHD) in children. Research highlights potential neurodevelopmental impacts, emphasizing the need for further investigation and regulation.
Area of Science:
- Environmental Health
- Neuroscience
- Pediatrics
Background:
- Attention deficit hyperactivity disorder (ADHD) prevalence is rising in children.
- Genetic and environmental factors are investigated as ADHD risk factors.
- Endocrine-disrupting chemicals (EDCs), including bisphenol A (BPA) and polychlorinated biphenyls (PCBs), are under scrutiny.
Purpose of the Study:
- To review studies published from 2013 to December 2023 on the potential impact of BPA and PCBs on ADHD.
- To synthesize current research on the association between EDC exposure and ADHD development.
Main Methods:
- Literature review of studies published between 2013 and 2023.
- Databases searched include Web of Science (WOS), PubMed, and Scopus.
- Focus on research exploring the link between BPA, PCBs, and ADHD.
Main Results:
- Prenatal exposure to bisphenol A (BPA) is associated with an increased risk of ADHD in offspring.
- Polychlorinated biphenyls (PCBs) are linked to cognitive and behavioral issues, including attention deficits.
- Both BPA and PCBs demonstrate neurodevelopmental disruption potential.
Conclusions:
- BPA and PCBs may pose a risk for ADHD development.
- Further research is needed to elucidate mechanisms and confirm the role of these EDCs.
- Regulation of BPA and PCBs is important for protecting children's neurodevelopmental health.
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