On the Typical Development of the Central Sulcus in Infancy: A Longitudinal Evaluation of Its Morphology and Link to Behaviour
Contact us if these videos are not relevant.
Contact us if these videos are not relevant.
View abstract on PubMed
Summary
This summary is machine-generated.Infant central sulcus (CS) folding rapidly evolves, reflecting asynchronous sensorimotor brain maturation. These changes may serve as early markers for neurodevelopmental progress.
Area Of Science
- Neuroscience
- Developmental Biology
- Radiology
Background
- Cortical folding, particularly the central sulcus (CS), is a key neurodevelopmental process beginning in gestation.
- The CS anatomically separates primary somatosensory and motor areas, making its development crucial for sensorimotor skill acquisition.
Purpose Of The Study
- To investigate asynchronous morphological changes along the CS in infants.
- To correlate these changes with the emergence of motor milestones.
Main Methods
- 3T anatomical MRI was used to analyze CS depth and curvature in 33 infants (1-3 months) and 23 adults.
- Four regions of interest (ROIs) along the CS, including the hand knob (HK) area, were examined for morphological evolution and interhemispheric asymmetry.
- The relationship between CS morphology and motor development (Bayley Scales) was explored.
Main Results
- No significant interhemispheric asymmetry in CS depth or curvature was found.
- All CS regions showed increased depth and curvature from 3 months to adulthood, with variability between 1 and 3 months.
- The central-medial and central-lateral regions exhibited the most consistent depth increases; motor development showed a trend with depth changes in the HK-related ROI.
Conclusions
- Rapid CS folding in infancy suggests asynchronous sensorimotor system maturation and differential cortical area growth.
- CS features show potential as early markers for sensorimotor development.
- Future studies combining anatomical and functional neuroimaging are recommended to further understand CS morphology and somatotopic organization.
Contact us if these videos are not relevant.
Contact us if these videos are not relevant.
Related Concept Videos
The human skull is composed of several bones that come together to protect the brain and support the structures of the face. The junctions where these bones meet are called sutures.
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
The main and largest component of the human brain is the cerebrum. The cerebrum consists of two main parts: the cerebral cortex, an outer layer with wrinkles or folds known as gyri and shallow grooves called sulci, and a deeper region beneath it. The cerebrum divides into two distinct hemispheres and contains five different lobes: the frontal, parietal, temporal, occipital, and insula. The central sulcus separates the frontal and parietal lobes and two functionally important gyri — the...
Socio-emotional development in infancy is primarily shaped by early emotional responses and social connections, with temperament playing a central role. Temperament refers to the consistent patterns in an individual's emotional and behavioral responses, observable even in infancy. By examining temperament, researchers can better understand an infant's unique ways of interacting with the world, influencing subsequent personality and socio-emotional growth.
Primary Temperament Types