A Rare Case of Brucellosis With Hepatic Involvement

Area of Science:

• Infectious Diseases
• Hepatology
• Public Health

Background:

• Brucellosis is a zoonotic infection caused by Brucella bacteria, posing a significant global public health risk.
• While uncommon in the U.S. due to animal health policies, it remains prevalent in other countries.
• Brucellosis often presents with non-specific symptoms, potentially leading to delayed diagnosis and multi-organ involvement.

Observation:

• A 58-year-old female presented with symptoms initially misdiagnosed, leading to significant hepatic involvement.
• The patient had a history of consuming unpasteurized dairy products imported from Mexico.
• Diagnosis was confirmed via blood cultures identifying Brucella species.

Findings:

• The patient received a combination therapy of doxycycline and gentamicin.
• Successful treatment led to the resolution of brucellosis and liver involvement.
• This case highlights the diagnostic challenges posed by nonspecific symptoms in brucellosis.

Implications:

• Clinicians should consider brucellosis in patients with nonspecific symptoms and a relevant travel or dietary history.
• Public health education on food safety, particularly regarding imported animal products, is essential.
• Prompt diagnosis and appropriate antibiotic regimens are critical for favorable outcomes in brucellosis cases.