Related Experiment Video
Updated: Sep 18, 2025

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors
Published on: May 17, 2024
A Rare Case of Granular Cell Tumor in the Groin: Importance of Excision With Negative Margins
Hui Un Kim1, Tyler Etwaroo2, Darren Williams1
1General Surgery, Western Reserve Health Education/NEOMED, Warren, USA.
Abstract:
Granular cell tumors (GCTs) are rare neoplasms of Schwann cell origin that typically arise in the head, neck, and tongue. We present a case of a 64-year-old female who presented with a left groin mass. Surgical excision was performed, and histopathological analysis confirmed a GCT without malignant features. However, the excised mass had positive margins, necessitating re-excision to minimize the risk of recurrence. Surgical excision with negative margins remains the primary treatment for GCTs. The case highlights the importance of recognizing GCTs in uncommon anatomical locations and the importance of complete surgical excision to prevent recurrence.

