Improving 24-Hour Medication Reconciliation Through Audit and Feedback: A Multicycle Quality Improvement Study at a

William Stanley1, Kate Falconer2, Megan Hume3

  • 1Emergency Medicine, Queensland Health, Rockhampton, AUS.

Cureus
|June 23, 2025
PubMed

Insights

A low-cost audit-feedback intervention significantly improved medication reconciliation (MR) documentation and the recording of reasons for withholding medications. This quality improvement project enhanced patient safety in a paper-based hospital setting.

Area of Science:

  • Healthcare Quality Improvement
  • Patient Safety
  • Clinical Pharmacy Practice

Background:

  • Medication reconciliation (MR) is a critical patient safety process during hospital admission, essential for accurate medication lists and reducing adverse events.
  • In paper-based systems, admitting clinicians primarily manage MR with limited pharmacy support, impacting compliance with national standards.
  • Assessing local MR compliance and evaluating interventions to improve documentation are vital for enhancing prescribing safety.

Purpose of the Study:

  • To evaluate compliance with national medication reconciliation (MR) benchmarks.
  • To assess the effectiveness of a structured audit-feedback intervention in improving MR documentation.
  • To determine if the intervention could enhance the recording of reasons for withholding medications.

Main Methods:

  • A quality improvement project utilized four 1-week periods: initial audit, pre-intervention baseline, post-intervention follow-up, and reaudit.
  • Reviewed medical records and prescription charts of 305 acute admissions within 24 hours of presentation.
  • Intervention involved personalized feedback, public recognition, and educational posters for admitting clinicians.

Main Results:

  • Documented MR increased significantly from 75.3% to 89.3% post-intervention (p=0.044) and 92.8% at reaudit (p=0.0049).
  • Proportion of withheld medications with documented reasons rose from 59.0% to 81.1% post-intervention (p=0.036) and remained elevated at 79.6% at reaudit (p=0.041).
  • Commonly withheld medications included diuretics, ACE inhibitors/ARBs, and statins; frequent reasons were acute kidney injury, dehydration, and hypotension.

Conclusions:

  • A targeted, low-cost audit-feedback intervention effectively improved medication reconciliation standards and documentation of withheld medications.
  • Behavioral strategies can yield significant improvements in prescribing safety, even in resource-limited, paper-based settings.
  • The intervention moved clinical practice closer to national standards for medication reconciliation.

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