Related Experiment Video
Updated: Sep 18, 2025

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
Published on: December 15, 2011
Intestinal celiac disease - related autoantibodies
Giorgia Fontana1, Fabiana Ziberna1, Egidio Barbi1
1Institute for Maternal and Child Health, I.R.C.C.S. Burlo Garofolo, Trieste, Italy.
None:
Celiac disease is a widespread autoimmune enteropathy with a genetic predisposition triggered by gluten intake. The only available treatment is a strict lifelong gluten-free diet. The diagnosis is based on the detection of serum celiac disease - related antibodies and histopathological analysis of duodenal biopsies. However, celiac disease has a wide spectrum of clinical, histological, and serological manifestations, and in some patients, the diagnosis can be challenging. Celiac disease - related antibodies antibodies are produced by intestinal B cells and can be detected in the small intestinal mucosa before their appearance in serum or before mucosal damage. In this paper, we reviewed the literature concerning the diagnostic value of intestinal celiac disease - related antibodies.
More Related Videos
Related Concept Videos
Gastritis-II: Pathophysiology
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Autoimmune Disorders
Concept and Mechanism of Autoimmune Diseases
The immune...
Transcytosis of IgG
IgG molecules from a mother undergo transcytosis starting around 13 weeks of gestation. The amount of IgG transferred and entering the fetal blood circulation increases with...
Drugs for Treatment of Crohn's Disease in IBD Using Biologic Agents: Anti-TNF

