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Updated: Sep 18, 2025

Design to Implementation Study for Development and Patient Validation of Paper-Based Toehold Switch Diagnostics
Published on: June 17, 2022
Choosing wisely: Improving decision-making for deployment of diagnostics in primary care settings
Varsha Shridhar1,2, Vasudha Kannan3, Ramakrishna Prasad2,4
1Molecular Solutions Care Health LLP, Bengaluru, India.
Primary care physicians need better guidance on selecting and using essential diagnostic tests. This study identifies key tests and challenges to improve diagnostic care in various settings.
Area of Science:
- Primary Care Medicine
- Diagnostic Technologies
- Health Services Research
Background:
- Essential diagnostics lists from WHO and ICMR lack specific guidance for primary care providers.
- Limited information exists on the practical aspects of diagnostic test selection and deployment in primary care.
Purpose of the Study:
- To identify essential diagnostic tests for primary care settings.
- To evaluate the availability, reliability, and usability of these tests.
- To understand challenges faced by primary care physicians in diagnostic test implementation.
Main Methods:
- Qualitative study involving interviews with 12 primary care physicians.
- Analysis of recorded, transcribed, and coded interview data.
- Literature review and data extraction on diagnostic tests.
Main Results:
- A list of diagnostic tests relevant for all primary care settings was developed.
- Tests required for specific settings (rural/urban, home/clinic, service scope, epidemiology) were identified.
- Physicians face challenges due to limited guidance on choosing and deploying diagnostics.
Conclusions:
- A comprehensive landscape analysis of diagnostics is crucial for primary care.
- This analysis will empower physicians to make informed decisions on diagnostic test selection and deployment.
- Improved guidance is needed to optimize diagnostic practices in primary care.
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