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Fission is the division of a single entity into two or more parts, which regenerate into separate entities that resemble the original. Organisms in the Archaea and Bacteria domains reproduce using binary fission, in which a parent cell splits into two parts that can each grow to the size of the original parent cell. This asexual method of reproduction produces cells that are all genetically identical.
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Changes in the environment of the early Earth drove the evolution of organisms. As prokaryotic organisms in the oceans began to photosynthesize, they produced oxygen. Eventually, oxygen saturated the oceans and entered the air, resulting in an increase in atmospheric oxygen concentration, known as the oxygen revolution approximately 2.3 billion years ago. Therefore, organisms that could use oxygen for cellular respiration had an advantage. More than 1.5 years ago, eukaryotic cells and...
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Assessing dual use research of concern (DURC)-lessons learned from the United States government institutional DURC policy.

Canadian journal of microbiology·2022
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Thrown in the Deep End: The Dual-Use Saga.

Rebecca L Moritz1

  • 1Tutela Strategies, LLC, Reno, NV, USA.

Applied Biosafety : Journal of the American Biological Safety Association
|June 23, 2025
PubMed
Summary

Biosafety professionals must proactively communicate and collaborate to manage complex research, ensuring safety and public trust. Transparency and integrated support systems are crucial for responsible scientific advancement.

Keywords:
biosafetydual-use research of concernpathogen of pandemic potentialscientific communicationtransparency

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Area of Science:

  • Biosafety and Biosecurity
  • Research Ethics
  • Public Health

Background:

  • Managing dual-use research presents significant ethical and safety challenges.
  • High-profile projects involving potential pandemic pathogens require careful oversight.
  • The role of biosafety professionals is evolving in complex research environments.

Purpose of the Study:

  • To share insights from managing dual-use research challenges.
  • To highlight the importance of communication, teamwork, and transparency.
  • To discuss the evolving role of biosafety professionals in research.

Main Methods:

  • Reflection on practical experience in biosafety management.
  • Analysis of responses to ethically complex research projects.
  • Identification of key lessons learned from managing public scrutiny and confidentiality.

Main Results:

  • Proactive communication, resilience, and team collaboration are essential.
  • Transparency is vital for fostering public trust.
  • Biosafety professionals are key partners in policy and responsible research practices.

Conclusions:

  • Continuous improvement in biosafety practices is necessary.
  • Integrated support systems are needed for complex biosafety and biosecurity challenges.
  • Biosafety professionals should be consulted in shaping research policies.