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What Does the Updated U.S. Dual-Use Research of Concern and Pathogens with Enhanced Pandemic Potential Policy Mean
1Biorisk Management, Asia Centre for Health Security, Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.
Introduction:
The U.S. government recently updated its policy for dual-use research of concern (DURC) and research involving pathogens with enhanced pandemic potential (PEPP). The policy comes into effect in May 2025.
Methods:
The U.S. policy covers the responsibilities for three major parties: principal investigators, research institutions, and Federal funding agencies. It outlines the criteria and provides examples of what constitutes Category 1 research (DURC) and Category 2 research (PEPP) and clarifies the process for developing and implementing risk mitigation plans. The relevance of this policy for research in Asia depends on local context and resources and its impact on changing biosecurity culture.
Conclusion:
This U.S. policy contributes substantially to the evolving international consensus that funders, research institutions, and researchers should implement enhanced oversight for DURC and PEPP. This is an important step forward for health security in Asia and globally.
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