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Chronic invasive fungal rhinosinusitis in a patient with chronic migraine
1Department of Critical Care Medicine, Naval Medical Center of PLA, China.
Abstract:
Chronic invasive fungal rhinosinusitis (CIFRS) is a rare disease caused by fungal infection and has an insidious course, which generally presents with headache at first, resulting in misdiagnosis and underestimation. Migraine is the most common primary headache and has symptoms mimicking rhinosinusitis. As a result, this may contribute to confusion of diagnosis when we consider the reason of headache, especially in patients suffering from migraine and rhinosinusitis at the same time. Here, we report a patient diagnosed with CIFRS and chronic migraine with the help of next-generation sequencing examination, to provide a reference in clinical treatment.
Insights
Chronic invasive fungal rhinosinusitis (CIFRS) can mimic migraine headaches, leading to misdiagnosis. Next-generation sequencing aided in diagnosing a patient with both CIFRS and chronic migraine, offering clinical treatment insights.
Area of Science:
- Otolaryngology
- Neurology
- Mycology
Background:
- Chronic invasive fungal rhinosinusitis (CIFRS) is a rare condition with insidious onset, often presenting as headache.
- Migraine is a common primary headache disorder that can present with symptoms overlapping those of rhinosinusitis.
- Simultaneous occurrence of CIFRS and migraine poses diagnostic challenges due to shared symptomatology.
Observation:
- A patient presented with symptoms suggestive of both rhinosinusitis and chronic migraine.
- Initial diagnostic considerations were complicated by the overlapping clinical presentations.
Findings:
- Next-generation sequencing (NGS) was instrumental in achieving a definitive diagnosis.
- The patient was concurrently diagnosed with chronic invasive fungal rhinosinusitis and chronic migraine.
Implications:
- This case highlights the importance of considering CIFRS in patients with chronic headaches, especially those with a history of migraine.
- NGS can be a valuable tool for diagnosing complex cases of fungal infections in the paranasal sinuses.
- Accurate diagnosis is crucial for appropriate clinical management and treatment of co-existing conditions.
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