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Updated: Aug 6, 2026
05:37
Cone Beam Intraoperative Computed Tomography-based Image Guidance for Minimally Invasive Transforaminal Interbody Fusion
Published on: August 6, 2019
6.5K
Novel Mini-open Transforaminal Lumbar Interbody Fusion
Kelv Shen1, Yuhang Ma2, Zhendong Huang1
1Department of Orthopedics, The Second Affiliated Hospital of Soochow University.
Journal of Visualized Experiments : Jove
|June 23, 2025
Summary
Mini-open transforaminal lumbar interbody fusion (MO-TLIF) offers a feasible surgical option for degenerative lumbar diseases. This modified technique demonstrates effectiveness with minimal muscle damage and improved patient outcomes.
Area of Science:
- Spine Surgery
- Orthopedics
- Minimally Invasive Procedures
Background:
- Transforaminal lumbar interbody fusion (TLIF) is a common procedure for spinal pathologies.
- Surgeons continually seek less invasive TLIF techniques, including open, minimally invasive, and endoscopic approaches.
Purpose of the Study:
- To describe a modified open TLIF using percutaneous pedicle screws (mini-open TLIF or MO-TLIF).
- To evaluate the feasibility and preliminary outcomes of the MO-TLIF procedure.
Main Methods:
- The MO-TLIF procedure was performed on over 300 patients since January 2021.
- Data collected included operation time, blood loss, ambulatory time, hematocrit, complications, VAS, ODI, paraspinal muscle cross-sectional area, and fusion rates via CT scans.
Main Results:
- Mean operation times were 102.3 min (single-level) and 130.2 min (multi-level).
- Average blood loss was 62.5 mL (single-level) and 108.3 mL (multi-level).
- Significant improvements in VAS and ODI scores were observed (p < 0.001), with minimal paraspinal muscle atrophy (2.5% symptomatic, 1.2% asymptomatic).
Conclusions:
- MO-TLIF is an effective and feasible technique for treating lumbar degenerative diseases, particularly multi-level conditions.
- The procedure is associated with minimal muscle damage and reduced operation times.
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