Related Experiment Video
Updated: Sep 18, 2025

Human Circadian Phenotyping and Diurnal Performance Testing in the Real World
Published on: April 7, 2020
Chronotype and Sleep Quality in College Students Undergoing Clinical Placement: A Moderated Moderation Model of Sleep
Renny Wulan Apriliyasari1,2,3, Jia-Wei Liu1,3, Chia-Wen Chou1
1School of Nursing, College of Nursing, Taipei Medical University, Taipei, Taiwan.
Background:
Chronotype, also referred to as morningness and eveningness, describes the natural preference of the body for wakefulness or sleep at different times during a 24-hour period. Individuals demonstrating late chronotypes and low resilience tend to have poor sleep quality, and the association between late chronotypes and sleep quality is known to be moderated by sleep reactivity. The mediating roles of sleep reactivity and psychological resilience in the association between chronotype and sleep quality in college students under situations of high stress have yet to be investigated.
Purpose:
This study was designed to evaluate the degree to which resilience moderates the moderating role of sleep reactivity on the association between chronotype and sleep quality in college students undergoing clinical placement.
Methods:
A cross-sectional study involving 225 college students undergoing clinical placement was conducted. The Chinese version of the Pittsburgh Sleep Quality Index was used to assess sleep quality, chronotype was assessed using the Morningness-Eveningness Questionnaire, sleep reactivity and resilience were respectively assessed using Ford's Insomnia Response to Stress Test and Brief Resilience Scale, and the SPSS PROCESS macro Version 4.3 (Hayes) was employed in moderated moderation analysis.
Results:
Resilience was shown to moderate the relationship between sleep reactivity and sleep quality (β=0.079, p =.039) as well as the moderating role of sleep reactivity in the chronotype-sleep quality relationship (β=-0.002, p =.027).
Conclusions:
In this study, sleep reactivity and chronotype both exhibited inverse effects on sleep quality in the moderate- and high-resilience groups. However, those in the low-resilience group with high sleep reactivity exhibited low sleep quality regardless of chronotype. Considering these findings, sleep reactivity and resilience should be adequately monitored during interventions designed to enhance sleep quality.
Related Concept Videos
Substance Use Disorders Affecting Sleep
Understanding the concepts of physical dependence,...
Insufficient Sleep and Sleep Deprivation
Sleep deprivation is a more severe form of sleep loss...
Circadian Rhythms and Gene Regulation
Understanding Sleep
The circadian rhythm, a nearly 24-hour cycle, is deeply influenced by environmental light cues. Light exposure directly affects the hypothalamus, which in turn regulates...
Chronopharmacokinetics: Circadian Rhythms and Influence on Drug Response
The time of drug administration is an important factor to consider, as it can influence the toxic dose of a drug. For example, a study conducted by Prins et al. in 1997 examined the effects of the timing of...
Management of Insomnia

