Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Role of Cerebellum and Prefrontal Cortex in Memory01:14

Role of Cerebellum and Prefrontal Cortex in Memory

606
The cerebellum, while traditionally associated with motor control, also plays a crucial role in memory, particularly in procedural memory, which involves learning motor tasks that become automatic through repetition. For example, studies have shown that when the cerebellum is damaged, individuals or animals lose the ability to learn conditioned motor responses, such as the conditioned eye-blink response in classical conditioning experiments with rabbits. This study demonstrates the...
606
Brainstem01:19

Brainstem

3.1K
The brainstem, located inferior to the brain and superior to the spinal cord, serves as a bridge between the cerebrum and the spinal cord. It plays a vital role in relaying information and controlling critical life functions. It comprises three primary regions: the midbrain, pons, and medulla oblongata.
The Midbrain
The midbrain is located beneath the diencephalon and connects the cerebrum with the lower parts of the brain. The cerebral peduncles are prominent midbrain structures that house the...
3.1K
Major Somatic Sensory Pathways01:28

Major Somatic Sensory Pathways

1.3K
Sensory impulses related to touch, pressure, vibration, and proprioception from various body parts, such as the limbs, trunk, neck, and posterior head, travel to the cerebral cortex through the posterior column-medial lemniscus pathway. The pathway’s name derives from the two white-matter tracts that convey the impulses: the spinal cord's posterior column and the brainstem's medial lemniscus. First-order sensory neurons extend their axons into the spinal cord, forming the...
1.3K
Cerebellum: Anatomical Regions01:17

Cerebellum: Anatomical Regions

2.3K
The cerebellum, also known as the "little brain," is located in the posterior cranial fossa, inferior to the tentorium cerebelli and dorsal to the brainstem. It plays a significant role in motor control, coordination, and proprioception.
Cerebellar Structure
Externally, the cerebellum features a highly convoluted surface with numerous folia (narrow ridges) separated by shallow sulci (grooves). The cerebellum is divided into two hemispheres by a thin median structure known as the vermis. The...
2.3K
Parkinson's Disease: Overview01:15

Parkinson's Disease: Overview

722
Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
722
Prosopagnosia01:24

Prosopagnosia

278
Prosopagnosia, also known as face blindness, is the inability to recognize faces. In severe cases, individuals with prosopagnosia may not recognize close family members, including parents and spouses, by their faces. For instance, someone with prosopagnosia might walk past their child in a crowd, only realizing their mistake upon noticing their child's distinctive backpack or favorite jacket. Prosopagnosia specifically impairs facial recognition, while the recognition of other objects or...
278

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Early neurological and developmental trajectories of infants at high risk of cerebral palsy in Bangladesh: a prospective longitudinal cohort study.

BMJ paediatrics open·2026
Same author

From waitlists to clinical action: pathway development and research priorities in childhood developmental regression.

The Lancet. Child & adolescent health·2026
Same author

Effectiveness and tolerability of cannabidiol in paediatric epilepsy: a one-year multisite prospective study.

Epilepsy & behavior : E&B·2026
Same author

KCNQ2 neonatal epilepsy: Impact of prompt diagnosis and treatment, and early predictors of outcome severity.

Epilepsia open·2026
Same author

Vision Intervention for Seeing Impaired Babies: Learning through Enrichment (VISIBLE) - protocol of a feasibility pilot randomised controlled trial.

BMJ open·2026
Same author

Triceps surae muscle architecture in ambulant children with cerebral palsy: architectural adaptations vary between children and muscles.

Journal of biomechanics·2026
Same journal

Inherited retinal degenerations: clinical phenotypes and emerging therapies.

Lancet (London, England)·2026
Same journal

Documenting hospice care.

Lancet (London, England)·2026
Same journal

After the wood chipper.

Lancet (London, England)·2026
Same journal

Assisted dying and the silencing of medicine's next generation.

Lancet (London, England)·2026
Same journal

Linguistic pragmatism: a woman with progressive abdominal pain in Thailand.

Lancet (London, England)·2026
Same journal

Medical compartmentalisation: a patient with chromosome 22q11.2 deletion syndrome in Japan.

Lancet (London, England)·2026
See all related articles

Related Experiment Video

Updated: Sep 18, 2025

A Battery of Motor Tests in a Neonatal Mouse Model of Cerebral Palsy
10:02

A Battery of Motor Tests in a Neonatal Mouse Model of Cerebral Palsy

Published on: November 3, 2016

24.6K

Cerebral palsy.

Iona Novak1, Michelle Jackman2, Megan Finch-Edmondson3

  • 1Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia; Cerebral Palsy Alliance Research Institute, Discipline of Child and Adolescent Health, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.

Lancet (London, England)
|June 23, 2025
PubMed
Summary
This summary is machine-generated.

Cerebral palsy (CP) is a physical disability impacting movement, with genetic factors playing a key role. Advances in early diagnosis and new therapies are improving outcomes, though prevalence varies globally.

More Related Videos

Event-related Potentials During Target-response Tasks to Study Cognitive Processes of Upper Limb Use in Children with Unilateral Cerebral Palsy
08:26

Event-related Potentials During Target-response Tasks to Study Cognitive Processes of Upper Limb Use in Children with Unilateral Cerebral Palsy

Published on: January 11, 2016

12.2K
Enhancing the Development and Growth of Infant Cerebral Palsy Rats Using Selective Spinal Manipulations
05:04

Enhancing the Development and Growth of Infant Cerebral Palsy Rats Using Selective Spinal Manipulations

Published on: February 2, 2024

685

Related Experiment Videos

Last Updated: Sep 18, 2025

A Battery of Motor Tests in a Neonatal Mouse Model of Cerebral Palsy
10:02

A Battery of Motor Tests in a Neonatal Mouse Model of Cerebral Palsy

Published on: November 3, 2016

24.6K
Event-related Potentials During Target-response Tasks to Study Cognitive Processes of Upper Limb Use in Children with Unilateral Cerebral Palsy
08:26

Event-related Potentials During Target-response Tasks to Study Cognitive Processes of Upper Limb Use in Children with Unilateral Cerebral Palsy

Published on: January 11, 2016

12.2K
Enhancing the Development and Growth of Infant Cerebral Palsy Rats Using Selective Spinal Manipulations
05:04

Enhancing the Development and Growth of Infant Cerebral Palsy Rats Using Selective Spinal Manipulations

Published on: February 2, 2024

685

Area of Science:

  • Neurology
  • Genetics
  • Developmental Pediatrics

Background:

  • Cerebral palsy (CP) is a permanent physical disability affecting movement and posture, stemming from early-life brain injuries or malformations.
  • Genetic factors are now understood to contribute to up to 30% of CP cases.
  • Prevalence rates have declined in high-income nations but remain higher in low- and middle-income countries.

Purpose of the Study:

  • To review recent advancements in the diagnosis, prevention, and management of cerebral palsy.
  • To highlight the impact of genetic contributions to CP.
  • To emphasize the need for lifelong care and address challenges faced by adults with CP.

Main Methods:

  • Review of current scientific literature and clinical evidence on cerebral palsy.
  • Analysis of trends in CP prevalence and diagnostic capabilities.
  • Synthesis of emerging therapeutic approaches, including medical, regenerative, and rehabilitation strategies.

Main Results:

  • Significant progress has been made in diagnosing CP as early as 3 months of age, enabling timely interventions.
  • New therapies are enhancing functional outcomes and participation for individuals with CP.
  • A genetic contribution is identified in a substantial portion of individuals with CP.
  • Prevalence has decreased by 40% in high-income countries, but remains higher in lower-income settings.

Conclusions:

  • Early diagnosis and intensive intervention significantly improve outcomes for children and families affected by cerebral palsy.
  • Emerging therapies offer new possibilities for enhancing function and participation throughout life.
  • A comprehensive, lifelong approach to care is essential for individuals with cerebral palsy, addressing their evolving health needs.