Related Experiment Video
Updated: Sep 18, 2025

Monitoring Lung Function with Electrical Impedance Tomography in the Intensive Care Unit
Published on: September 6, 2024
Patterns of lung aeration assessed through electrical impedance tomography in paediatric patients undergoing elective
Daniela Rosalba1,2, Grazia Meneghetti2, Federico Verdina1,2
1Department of Traslational Medicine, Università del Piemonte Orientale, Novara, Italy.
Insights
Controlled mechanical ventilation (CMV) in pediatric surgery shifts ventilation to lung centers, unlike spontaneous breathing. This effect reverses upon recovery, highlighting anesthesia
Area of Science:
- Anesthesiology
- Pediatric Surgery
- Respiratory Physiology
Background:
- Anesthesia's impact on pediatric lung function is under investigation.
- Optimizing pulmonary management in pediatric surgery requires understanding respiratory mechanics.
Purpose of the Study:
- To assess ventilation distribution changes during anesthesia in pediatric patients.
- Utilize electrical impedance tomography (EIT) to evaluate ventilation patterns.
Main Methods:
- Observational study of 76 pediatric surgical patients (57 CMV, 19 spontaneous breathing).
- Electrical impedance tomography (EIT) monitored lung ventilation at multiple time points.
- Analyzed regional ventilation distribution and center of ventilation (CoV).
Main Results:
- Controlled mechanical ventilation (CMV) caused a progressive shift of ventilation to ventral lung regions.
- Ventilation decreased in dorsal lung zones during CMV.
- Center of ventilation (CoV) shifted to non-dependent lung regions during CMV.
- No significant ventilation changes were observed in spontaneously breathing patients.
Conclusions:
- CMV in pediatric surgery induces ventral lung ventilation redistribution, unlike spontaneous breathing.
- These ventilation changes are reversible upon recovery of spontaneous breathing.
Background:
The impact of anaesthesia on lung function during paediatric surgery remains an area of active investigation. Understanding respiratory mechanics under different anaesthetic approaches is crucial for optimising pulmonary management in this vulnerable population.
Objective:
To assess ventilation distribution changes during different phases of anaesthesia in paediatric patients, using electrical impedance tomography (EIT).
Methods:
This observational study included 76 paediatric surgical patients-57 under controlled mechanical ventilation (CMV) and 19 breathing spontaneously. EIT assessed lung ventilation at multiple timepoints (T1-T6), analyzing regional distribution (ROIs) and center of ventilation (CoV).
Results:
In the CMV group, ventilation progressively shifted toward ventral lung regions (p < 0.0001 from T1 to T2, T3, T4, T5) with a contemporaneously reduced ventilation switching from T1 to T2 (p = 0.005), T3 (p < 0.0001), T4 (p = 0.001), and T5 (p < 0.0001). Ventilation normalised upon restoration of spontaneous breathing at the end of surgery. In the same group, CoV shifted toward non-dependent lung regions from T1 to T2, T3, T4, and T5 (p < 0.0001) and returned to baseline at T6. Overall, no modifications were observed in the spontaneous breathing group.
Conclusions:
In paediatric surgical patients, contrariwise to spontaneous breath where no modifications occurred, CMV induced a progressive redistribution of ventilation towards the ventral lung regions, at the expense of the dorsal zones. These changes were reversible with the recovery of spontaneous breathing.
Trial Registration:
NCT06370507.
More Related Videos
14:49Conducting Respiratory Oscillometry in an Outpatient Setting
Published on: April 8, 2022
08:30Intraperitoneal Glucose Tolerance Test, Measurement of Lung Function, and Fixation of the Lung to Study the Impact of Obesity and Impaired Metabolism on Pulmonary Outcomes
Published on: March 15, 2018
Related Concept Videos
Assessment of Ventilation II: Respiratory Depth and Rhythm
Respiratory depth measures the volume of air inhaled or exhaled during a breath. It can vary from shallow to deep and typically remains consistent when a person is at rest or asleep. Occasionally, individuals will automatically inhale deeply, known as sighing, which inflates the lungs with more air than normal breathing.
To assess respiratory depth, observe the degree of chest excursion or movement:
Physical Assessment of the Respiratory Tract II: Inspection
Chest Configuration
The chest configuration...
Assessment of Respiration
Subjective Assessment: Nurses interview the patient to gather information directly during the subjective assessment. It includes questions about the individual's medical history, medications, and symptoms, focusing on past respiratory conditions like...
Pneumothorax-II
Clinical Manifestations: