Long-Term Complications and Quality of Life After Urinary Diversion for Bladder Cancer: A Systematic Review and Meta-Analysis
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View abstract on PubMed
Summary
This summary is machine-generated.This review compares long-term outcomes of urinary diversion after radical cystectomy for bladder cancer. Ileal conduit (IC) showed fewer stones, while orthotopic neobladder (ONB) offered better function and body image.
Area Of Science
- Urology
- Oncology
- Surgical Outcomes
Background
- Radical cystectomy (RC) for bladder cancer necessitates urinary diversion, impacting long-term patient health and quality of life (QoL).
- Choosing the optimal urinary diversion technique is crucial for managing post-surgical complications and patient well-being.
Purpose Of The Study
- To systematically review and meta-analyze long-term complications (≥5 years post-RC) across major urinary diversion types.
- To compare morbidity, mortality, reoperation rates, infections, and QoL among ileal conduit (IC), orthotopic neobladder (ONB), and continent cutaneous urinary diversion (CCUD).
Main Methods
- Systematic review and meta-analysis of 16 studies including 8,493 patients undergoing RC.
- Comparison of outcomes based on diversion type: IC, ONB, and CCUD.
- Assessment of urinary tract infections, stone formation, reoperations, and patient-reported QoL.
Main Results
- Ileal conduit (IC) was linked to reduced urinary stone formation and superior global health scores.
- Orthotopic neobladder (ONB) demonstrated better urinary function and body image perception.
- Continent cutaneous urinary diversion (CCUD) data were limited for meta-analysis, but qualitative insights suggested potential functional and QoL advantages over IC and ONB.
Conclusions
- Individualized surgical decisions for urinary diversion should prioritize long-term outcomes and patient preferences.
- Further high-quality research is essential to fully elucidate the long-term safety, functional results, and QoL implications of CCUD.
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