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Recurrence of Obstructive Sleep Apnea in Post-adenotonsillectomy Obese Pediatric Patients: A Systematic Review
Adi Cohen1, Andrew Gunthner1, Adam Cervone1
1Medicine, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Davie, USA.
Insights
Obstructive sleep apnea (OSA) frequently recurs in obese children after adenotonsillectomy (AT). Obesity is a significant risk factor for residual disease, indicating AT alone is often insufficient for resolution.
Area of Science:
- Pediatric Pulmonology
- Otolaryngology
- Obesity Medicine
Background:
- Obstructive sleep apnea (OSA) is a common complication of pediatric obesity.
- Adenotonsillectomy (AT) is the primary surgical treatment for pediatric OSA.
- Recurrence of OSA post-AT in obese children raises concerns about treatment efficacy.
Purpose of the Study:
- To systematically review the recurrence of OSA in obese pediatric patients following AT.
- To identify key risk factors associated with residual OSA post-AT in this population.
Main Methods:
- Systematic literature search of Embase, PubMed, and Web of Science.
- Inclusion of peer-reviewed articles from the last five years on pediatric patients (<18 years) with BMI ≥ 95th percentile, diagnosed with OSA/sleep-disordered breathing preoperatively, and who underwent AT.
- Analysis of eleven eligible studies.
Main Results:
- 82% of studies showed a significant link between obesity and OSA recurrence after AT.
- Higher baseline apnea-hypopnea index, postoperative weight gain, and residual upper airway obstruction were key risk factors.
- Two studies showed contradictory results, but had limitations.
Conclusions:
- Adenotonsillectomy alone is frequently insufficient for resolving OSA in obese pediatric patients.
- High recurrence rates necessitate a multidisciplinary approach, including weight management and non-invasive ventilation.
- Improved outcomes require integrated care strategies for this vulnerable population.
Abstract:
Obstructive sleep apnea (OSA) is an under-recognized consequence of pediatric obesity, with adenotonsillectomy (AT) serving as the standard first-line surgical treatment. In obese pediatric patients, OSA often recurs postoperatively, raising concern for the long-term efficacy of AT. This systematic review evaluates the recurrence of OSA in post-AT obese pediatric patients, with a focus on the key risk factors contributing to residual disease. A literature search was conducted using Embase, PubMed, and Web of Science. Eligibility criteria included peer-reviewed, English articles published within the last five years that contained pediatric patients less than 18 years old who had a body mass index (BMI) ≥ 95th percentile. All patients had to have been diagnosed with sleep-disordered breathing or OSA preoperatively and must have undergone AT. Eleven studies met these criteria, of which 82% demonstrated a significant association between obesity and recurrence of OSA following AT. Key factors included higher baseline apnea-hypopnea index, postoperative weight gain, and residual upper airway obstruction. Two studies contradicted this trend, but limitations such as the use of subjective questionnaires and short follow-up durations reduced the studies' reliability. The findings indicate that AT alone is often insufficient in resolving OSA in obese pediatric patients. Given the high recurrence rates, a multidisciplinary approach, including weight management and non-invasive ventilation, may be needed to improve outcomes in this vulnerable population.
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