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Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA
Published on: February 9, 2011
Spontaneous Necrotizing Soft Tissue Infection and Fatal Clostridium septicum Septicemia in Myelodysplastic Syndrome:
Ifeoma Achebe1, Chioma Nwachukwu2, Chukwuemeka Nzewi3
1Internal Medicine, Genesis Health System, Davenport, USA.
Abstract:
Necrotizing soft tissue infection (NSTI) is a rare but life-threatening disease characterized by rapid spread and necrosis of the skin, subcutaneous tissue, fascia, and muscle. We present a fatal case of atraumatic NSTI involving the left lower extremity in an 80-year-old female with advanced myelodysplastic syndrome. Blood cultures grew Clostridium septicum and Staphylococcus epidermidis, the latter thought to be a blood contaminant. The patient rapidly progressed to septic shock and died within 34 hours of presentation. Our case emphasizes the need for a high index of suspicion for NSTI in patients with advanced malignancies.
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