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Related Concept Videos

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Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
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Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
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Related Experiment Video

Updated: Sep 18, 2025

A Mouse Model of Intestinal Partial Obstruction
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Two Cases of Small Intestinal Follicular Lymphoma Presenting with Intestinal Stricture.

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Primary gastrointestinal follicular lymphoma (FL) rarely causes intestinal stricture. Surgical resection of small intestinal FL provided diagnostic clarity and symptom relief in two patients.

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Area of Science:

  • Gastroenterology
  • Hematology
  • Oncology

Background:

  • Primary gastrointestinal follicular lymphoma (FL) is a rare malignancy.
  • Intestinal stricture is an uncommon presentation of FL.

Observation:

  • Two cases of small intestinal FL presenting with obstructive symptoms due to stricture are described.
  • Case 1: A 63-year-old male with ileal FL causing obstruction.
  • Case 2: A 79-year-old female with concurrent jejunal FL and colon adenocarcinoma causing jejunal strictures.

Findings:

  • Immunohistochemical analysis confirmed FL (CD10+, CD20+, BCL-2+) in both cases.
  • Surgical resection was curative for the FL in both patients.
  • No residual lymphoma was detected postoperatively via PET-CT.

Implications:

  • These cases underscore the importance of considering FL in the differential diagnosis of unexplained intestinal strictures.
  • Surgical intervention offers both diagnostic and therapeutic benefits for symptomatic gastrointestinal FL.
  • Tailored postoperative management based on individual patient factors and disease status is crucial.