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Updated: Sep 18, 2025

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
Published on: August 8, 2025
Feasibility of guiding catheter exchange using extension wire in percutaneous coronary intervention after
Makoto Saigan1, Masaki Miyasaka1,2, Daishi Tazawa1
1Department of Cardiovascular Medicine, Sendai Kousei Hospital, 1-20 Tsutsumidori-Amamiya, Aoba Ward, Sendai, Miyagi, 9810914, Japan.
Insights
An extension wire (EW) successfully facilitated diagnostic catheter (DC) to guiding catheter (GC) exchange in all 11 percutaneous coronary intervention (PCI) cases post-transcatheter aortic valve replacement (TAVR). This approach offers a feasible solution for complex PCI procedures after TAVR.
Area of Science:
- Interventional Cardiology
- Cardiovascular Devices
- Structural Heart Disease
Background:
- Transcatheter aortic valve replacement (TAVR) is a common procedure for aortic stenosis.
- Percutaneous coronary intervention (PCI) following TAVR presents unique challenges due to the presence of the transcatheter heart valve (THV).
- Engaging coronary arteries after TAVR often requires specialized techniques to navigate the THV.
Purpose of the Study:
- To evaluate the feasibility and success of using an extension wire (EW) for diagnostic catheter (DC) to guiding catheter (GC) exchange during PCI after TAVR.
- To assess the procedural outcomes and effectiveness of this technique in complex coronary interventions.
Main Methods:
- A retrospective analysis of 11 PCI cases performed after TAVR between January 2020 and June 2024.
- Utilized an extension wire (EW) to facilitate the transition from a diagnostic catheter (DC) to a guiding catheter (GC).
- Reviewed clinical, angiographic, and procedural data, defining success as successful DC-to-GC exchange and completion of PCI.
Main Results:
- The EW-assisted DC-to-GC exchange was successful in all 11 cases (100%).
- Successful revascularization was achieved in 10 out of 11 patients (91%).
- Lesions were complex (ACC/AHA Type B2/C), and various THV types (SAPIEN, Evolut, Navitor) and guiding catheters were used.
Conclusions:
- The use of an extension wire (EW) is a feasible and highly successful method for facilitating diagnostic catheter (DC) to guiding catheter (GC) exchange during PCI after TAVR.
- This technique simplifies complex PCI procedures in patients with a transcatheter heart valve (THV).
- Employing an EW optimizes procedural outcomes and offers a valuable approach for interventional cardiologists managing post-TAVR PCI.
Abstract:
Percutaneous coronary intervention (PCI) after transcatheter aortic valve replacement (TAVR) is technically challenging because of the presence of the transcatheter heart valve (THV), which complicates coronary artery engagement. Owing to their flexibility, diagnostic catheters (DCs) facilitate coronary access, but require subsequent exchange to guiding catheters (GCs) for PCI. The feasibility of using an extension wire (EW) to facilitate DC-to-GC exchange in this context remains unexplored. A retrospective analysis was conducted at our institution, examining 11 PCI cases performed after TAVR between January 6, 2020, and June 1, 2024, in which an EW was employed to transition from a DC to a GC. Clinical, angiographic, and procedural data were reviewed. Procedural success was defined as a successful DC-to-GC exchange and completion of PCI. DC-to-GC exchange using an EW was successfully achieved in all 11 cases (100%). Revascularization was achieved in 10/11 cases (91%). The lesions were uniformly classified as American College of Cardiology/American Heart Association Type B2/C. The GCs included Judkins-type in 7/11 cases (64%) and backup-type in 4/11 cases (36%). The THV types included SAPIEN in 6/11 cases (55%), Evolut in 3/11 cases (27%), and Navitor in 2/11 cases (18%). A 6Fr GC was utilized in 10/11 cases (91%), and rotational atherectomy was performed in 1/11 cases (9%). The use of an EW to facilitate the transition from DC to GC in PCI after TAVR resulted in high procedural success, providing a feasible approach for addressing complex lesions and optimizing procedural outcomes.
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