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Published on: December 9, 2022
EUS-guided ethanol ablation in patients with solid pseudopapillary neoplasm: a four-case series
Yousik Myung1, Kazuo Hara2, Shin Haba1
1Department of Gastroenterology, Aichi Cancer Center, 1-1 Kanokoden, Chikusa-ku, Nagoya, 464-8681, Japan.
Background/Aims:
Solid pseudopapillary neoplasm (SPN) of the pancreas is a rare tumor with low malignant potential, though 10-15% may show invasive or metastatic behavior. This study aimed to evaluate the safety and efficacy of endoscopic ultrasound-guided ethanol ablation (EUS-EI) in patients with SPN who were not surgical candidates.
Methods:
Four patients with SPN who declined or were ineligible for surgery underwent EUS-EI at Aichi Cancer Center. Technical and clinical outcomes, as well as adverse events, were assessed.
Results:
Technical success was achieved in all patients (100%). Clinical success was observed in three patients (75%), including two with complete ablation and one with significant tumor reduction. No major adverse events or tumor recurrence occurred during follow-up.
Conclusions:
EUS-EI may be a safe and effective alternative for managing SPN in non-surgical candidates.
