Pregnancy Outcomes After One Anastomosis Gastric Bypass

Area of Science:

• Bariatric Surgery
• Maternal-Fetal Medicine
• Reproductive Endocrinology

Background:

• One anastomosis gastric bypass (OAGB) is increasingly prevalent globally.
• Limited data exists on pregnancy outcomes following OAGB surgery.
• This study investigates maternal and perinatal outcomes in OAGB patients.

Purpose of the Study:

• To evaluate the association between OAGB and maternal health during pregnancy.
• To assess perinatal outcomes in infants born to mothers who underwent OAGB.
• To compare outcomes between OAGB patients and a matched control group.

Main Methods:

• A cohort of 50 women who delivered after OAGB (2017-2024) was compared to 50 matched controls.
• Matching criteria included preoperative BMI, age, delivery history, and delivery year.
• Maternal and perinatal data were collected and analyzed.

Main Results:

• OAGB group had significantly lower rates of gestational hypertensive disorders (2% vs. 10%) and gestational diabetes mellitus (4% vs. 18%).
• Lower hemoglobin levels and higher rates of IV iron supplementation were observed in OAGB patients.
• OAGB infants showed lower birthweight (2900g vs. 3392g) and increased small-for-gestational-age rates (28% vs. 6%).

Conclusions:

• OAGB is linked to reduced gestational diabetes, hypertensive disorders, and excessive fetal growth.
• Increased rates of small-for-gestational-age infants and lower maternal hemoglobin levels are associated with OAGB.
• Careful monitoring for anemia and fetal growth is crucial for OAGB pregnancies.