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Enterocolic lymphocytic phlebitis: Clinical insights from a literature review
Ying Zhao1, Xiaoying Zhang2, Yongsheng Li3
1Central Laboratory, The Affiliated Panyu Central Hospital, Guangzhou Medical University, Guangzhou, China.
Objective:
Enterocolic lymphocytic phlebitis (ELP) is a rare venous-specific gastrointestinal inflammation with challenging preoperative diagnosis. We aimed to characterize its clinicopathological spectrum.
Patients And Methods:
This narrative review synthesizes evidence from 85 published cases (9-81 years) from 50 articles to characterize ELP's clinicopathological features and diagnostic pitfalls, along with its differentiation from other vasculitides, such as Behcet's disease, systemic lupus erythematosus, mesenteric inflammatory veno-occlusive disease, idiopathic myointimal hyperplasia of the mesenteric veins and IgG4-related diseases.
Results:
ELP has a wide range of clinical and histological presentations, it predominantly affects the right colon/small bowel, mimicking acute abdomen. Diagnosis relies on postoperative histopathology showing venular lymphocytic infiltration.
Conclusion:
ELP represents a underdiagnosed clinicopatologic entity, a diagnosis of ELP is predominantly made after histological resection.
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