Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Thermoregulation01:26

Thermoregulation

1.4K
The human body has a sophisticated thermoregulation system that employs negative feedback mechanisms to maintain an optimal core temperature. When the core temperature drops, peripheral and central thermoreceptors send signals to the hypothalamus, activating the heat-promoting center. This center triggers several responses aimed at increasing the core temperature. First, vasoconstriction reduces the flow of warm blood from internal organs to the skin so that the heat is not lost from the skin,...
1.4K
What is Homeostasis?01:16

What is Homeostasis?

45.6K
Maintaining homeostasis requires that the body continuously maintain its internal conditions. Each physiological condition has a particular set point, from body temperature to blood pressure to levels of certain nutrients. A set point is the physiological value around which the normal range fluctuates. A normal range is a restricted set of values that is optimally healthful and stable. For example, the set point for normal human body temperature is approximately 37°C (98.6°F).
45.6K
Mechanism of heat transfer01:19

Mechanism of heat transfer

1.4K
Understanding heat transfer mechanisms is essential for understanding how our bodies maintain balance in different environmental conditions. When the environment is thermoneutral, the body is in a state of balance, neither using nor releasing energy to maintain its core temperature. However, when the environment is not thermoneutral, the body employs four heat transfer mechanisms to maintain homeostasis: conduction, convection, evaporation, and radiation. These mechanisms facilitate heat...
1.4K
Body Temperature01:25

Body Temperature

3.1K
The body's temperature, measured in degrees, is determined by the balance between heat production and dissipation to the surrounding environment. For instance, if exercising vigorously, the body will produce more heat, causing sweat and dissipating that heat. Despite extreme environmental conditions and physical exertion, the human temperature-control system maintains a constant core body temperature (the temperature of deep tissues, which are the tissues located beneath the skin and other...
3.1K
Mechanisms of Heat Transfer01:14

Mechanisms of Heat Transfer

584
Heat transfer between the human body and its environment occurs through four main mechanisms: conduction, convection, radiation, and evaporation.
Conduction, accounting for approximately 3% of body heat loss at rest, is the process of exchanging heat between molecules of two materials in direct contact. This can result in both heat loss and gain. For instance, when the body is submerged in water, which conducts heat 20 times more effectively than air, it can either lose or gain significant...
584
Other Factors Affecting Respiration Centers01:17

Other Factors Affecting Respiration Centers

973
Breathing is primarily an involuntary activity regulated by the brainstem respiratory centers. However, it can also be consciously controlled, allowing us to hold our breath or take deeper breaths when needed. This voluntary control is facilitated by the cerebral motor cortex, which bypasses the medullary centers to stimulate the respiratory muscles directly.
However, the ability to hold one's breath voluntarily is not limitless. When the CO2 concentration in the blood reaches a critical...
973

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sex Differences in the Effects of Etonogestrel on Respiratory Recovery in an In Vivo Rat Model of Central Chemoreflex Impairment.

Acta physiologica (Oxford, England)·2026
Same author

Sex-specific impact of early life stress on adult lung inflammatory response after LPS and Poly I:C exposures.

Brain, behavior, & immunity - health·2026
Same author

Early life stress and disruption of the ageing trajectory in female rats: Insights into the origins and mechanisms underlying the risk of hypertension.

Experimental physiology·2026
Same author

Ageing reveals the latent effects of early life stress on respiratory and metabolic function in female rats: Novel insights into the sex-specific origins of sleep apnoea.

Experimental physiology·2025
Same author

Early life stress and hormonal status influence orexin-1 receptor expression in structures regulating cardiorespiratory responses to CO<sub>2</sub>.

Experimental physiology·2025
Same author

Knockdown of PHOX2B in the retrotrapezoid nucleus reduces the central CO<sub>2</sub> chemoreflex in rats.

eLife·2024

Related Experiment Video

Updated: Sep 18, 2025

Determining Basal Energy Expenditure and the Capacity of Thermogenic Adipocytes to Expend Energy in Obese Mice
06:57

Determining Basal Energy Expenditure and the Capacity of Thermogenic Adipocytes to Expend Energy in Obese Mice

Published on: November 11, 2021

5.6K

Homeostasis: Stay cool but keep on breathing.

Tara A Janes1, Richard Kinkead2

  • 1Department of Physiology, Women and Children's Health Research Institute, University of Alberta, Edmonton, AB, Canada.

Current Biology : CB
|June 24, 2025
PubMed
Summary
This summary is machine-generated.

Temperature directly influences neural circuits controlling breathing. This study shows environmental factors, like temperature, can regulate essential physiological functions in frogs, impacting neural network activity.

More Related Videos

Field-Based Thermal Physiology Assay: Cold Shock Recovery under Ambient Conditions
07:54

Field-Based Thermal Physiology Assay: Cold Shock Recovery under Ambient Conditions

Published on: March 9, 2021

3.1K
An Automated Method to Determine the Performance of Drosophila in Response to Temperature Changes in Space and Time
06:52

An Automated Method to Determine the Performance of Drosophila in Response to Temperature Changes in Space and Time

Published on: October 12, 2018

6.5K

Related Experiment Videos

Last Updated: Sep 18, 2025

Determining Basal Energy Expenditure and the Capacity of Thermogenic Adipocytes to Expend Energy in Obese Mice
06:57

Determining Basal Energy Expenditure and the Capacity of Thermogenic Adipocytes to Expend Energy in Obese Mice

Published on: November 11, 2021

5.6K
Field-Based Thermal Physiology Assay: Cold Shock Recovery under Ambient Conditions
07:54

Field-Based Thermal Physiology Assay: Cold Shock Recovery under Ambient Conditions

Published on: March 9, 2021

3.1K
An Automated Method to Determine the Performance of Drosophila in Response to Temperature Changes in Space and Time
06:52

An Automated Method to Determine the Performance of Drosophila in Response to Temperature Changes in Space and Time

Published on: October 12, 2018

6.5K

Area of Science:

  • Neuroscience
  • Physiology
  • Environmental Science

Background:

  • Homeostatic control of neural networks relies on monitoring and adjusting neuronal activity and excitability.
  • The direct impact of the physical environment on neural regulation of vital functions is not fully understood.

Purpose of the Study:

  • To investigate the direct effect of environmental temperature on neural circuits controlling breathing.
  • To explore how physical environmental factors can modulate neural network activity.

Main Methods:

  • Utilized frog models to study neural circuits.
  • Manipulated ambient temperature to observe effects on neural activity related to respiration.

Main Results:

  • Demonstrated that temperature directly regulates the neural circuits responsible for breathing in frogs.
  • Showcased a direct link between physical environment and physiological regulation at the neural level.

Conclusions:

  • Environmental temperature is a direct regulator of respiratory neural circuits.
  • Neural networks are sensitive to physical environmental parameters, influencing fundamental physiological processes.