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Trichosporon infection in a cat
Journal of the American Veterinary Medical Association
|November 1, 1985
Summary
A feline nasal mass was identified as a Trichosporon pullulans fungal infection. Initial treatment with ketoconazole was partially effective but led to liver toxicity, with subsequent therapies proving unsuccessful.
Area of Science:
- Veterinary Mycology
- Feline Infectious Diseases
Background:
- Nasal masses in cats can present with diverse clinical signs including discharge and fever.
- Accurate diagnosis is crucial for effective treatment of complex feline conditions.
Observation:
- A domestic shorthair cat presented with a protruding nasal mass, nasal discharge, and recurrent fever.
- Cytologic, histologic, and fungal culture methods confirmed Trichosporon pullulans infection.
Findings:
- Initial oral ketoconazole treatment reduced the nasal mass but caused hepatotoxicosis.
- Altering the ketoconazole regimen led to mass regrowth.
- Subsequent treatment with amphotericin B and 5-flucytosine was ineffective.
Implications:
- Trichosporon pullulans is a rare but significant cause of nasal mycosis in cats.
- Treatment of feline nasal fungal infections can be challenging, requiring careful consideration of drug toxicity and efficacy.
- This case highlights the need for further research into effective therapeutic strategies for such infections.