Effectiveness of an online mindfulness-based stress-reduction intervention to reduce anxiety in breast cancer
Ana Ferrigno Guajardo1, Misael Salazar-Alejo2, Fernanda Mesa-Chavez2
1Department of Medicine, Yale University School of Medicine, New Haven, CT, USA.
Purpose:
This study evaluated the efficacy of an online mindfulness-based stress reduction (MBSR) intervention in reducing anxiety among breast cancer (BC) survivors, leveraging the potential advantages of digital delivery to enhance psychosocial care for this population.
Methods:
In this randomized controlled trial, 68 BC survivors with elevated anxiety levels were assigned to either an 8-week online MBSR intervention (n = 33) or a waitlist control group (n = 35). Anxiety (GAD-7), depression (PHQ-9), fatigue (FACIT-F), insomnia (ISI), cancer-related worry (CWS), vasomotor symptoms (MENQOL), and mindful awareness (MAAS) were assessed at baseline, post-intervention, and at 5- and 8-months follow-up.
Results:
Compared to the control group, MBSR participants showed significant reductions in anxiety (mean difference -4.13 points, 95CI -6.79 to -1.46, p = 0.003), depression (mean score difference -6.03, p < 0.001), fatigue (mean difference + 6.03, p = 0.002), insomnia (mean difference -3.97, p = 0.026), and cancer-related worry (mean difference -4.57, p = 0.003) at post-intervention, but no change in vasomotor symptoms (p > 0.05). MBSR participants also demonstrated increased mindful awareness (mean difference + 1.00, p = 0.004) that persisted through follow-up. The proportion of participants with clinically significant anxiety decreased from 96% pre-intervention to 38% at 8-months follow-up in the MBSR group, compared to relatively stable rates (88% to 87%) in the control group.
Conclusions:
Online MBSR is a potentially effective intervention for reducing anxiety and improving psychological well-being in BC survivors. This accessible format may help overcome barriers to psychosocial care for cancer survivors.
Gov Id:
NCT05837169.
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