Related Experiment Video
Updated: Sep 18, 2025

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression
Published on: April 26, 2024
Association between vitamin D level and sleep quality in the elderly population: a prospective cohort study
Wei-Hsuan Lee1,2, Yu-Hsi Chen1,2, Tsai-Yu Wang1
1Department of Pulmonary and Critical Care Medicine, Sleep Center, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Purpose:
Vitamin D is essential not only for skeletal health but also for regulating sleep. Recent studies suggest a link between vitamin D deficiency and poor sleep quality, including lower sleep efficiency and shorter sleep duration. This study aimed to investigate the relationship between sleep quality and serum vitamin D levels in healthy elderly individuals.
Methods:
This study examined the association between serum vitamin D levels and sleep quality in individuals aged 60 years and above residing in Taipei's Health & Culture Village and Active Aging Center. A total of 465 participants were enrolled, with those exhibiting specific organ abnormalities or dysfunctions excluded. Sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI), and vitamin D levels were measured using enzyme-linked immunosorbent assay (ELISA). The relationships between vitamin D levels and PSQI scores were analyzed, with a focus on the daytime dysfunction component of the PSQI.
Results:
Among the seven domains of the PSQI, the daytime dysfunction domain had the strongest statistical association with serum vitamin D levels (p = 0.044). Participants without daytime dysfunction had significantly higher vitamin D levels than did those with daytime dysfunction (p = 0.04). No significant associations were detected between vitamin D levels and other factors, such as sex or age.
Conclusions:
Higher serum vitamin D levels are associated with better sleep quality in elderly individuals, particularly in those without daytime dysfunction. This finding highlights the potential importance of maintaining adequate vitamin D levels to promote healthy sleep patterns in older adults.
Related Concept Videos
Substance Use Disorders Affecting Sleep
Understanding the concepts of physical dependence,...
Insufficient Sleep and Sleep Deprivation
Sleep deprivation is a more severe form of sleep loss...
Role of Skin in Vitamin D Synthesis
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
Correlations
Role of Vitamins in Maintaining Bone Health
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Management of Insomnia

