Related Experiment Video
Updated: Sep 18, 2025

Local Anesthetic Thoracoscopy for Undiagnosed Pleural Effusion
Published on: November 10, 2023
Experience with etilefrine in refractory non-traumatic chylothorax: a case report
Ryo Sakai1,2, Kazuhiro Shiraga1, Ryo Inuzuka1
1Department of Pediatrics, The University of Tokyo Hospital, Tokyo, Japan.
Abstract:
Noonan syndrome is associated with lymphatic system structural abnormalities and may present with potentially fatal refractory chylothorax. We report a 2-year-old boy with Noonan syndrome with non-traumatic chylothorax who was refractory to dietary therapy with medium-chain triglyceride milk, octreotide, prednisolone, lymphatic embolisation, and lymphatico-venous anastomosis but improved with etilefrine administration. Etilefrine may be a treatment option for paediatric chylothorax, regardless of the aetiology.
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