Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Wall motion in expiratory flow limitation: choke and flutter.

P M Webster, R P Sawatzky, V Hoffstein

    Journal of Applied Physiology (Bethesda, Md. : 1985)
    |October 1, 1985
    PubMed
    Summary

    Airway flow limitation, previously explained by wave speed, may involve aerodynamic flutter. This mechanism explains energy dissipation and the pure tone heard during maximal expiratory airflow.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Real world data on outcomes of anti-CD38 antibody treated, including triple class refractory, patients with multiple myeloma: a multi-institutional report from the Canadian Myeloma Research Group (CMRG) Database.

    Blood cancer journal·2023
    Same author

    Percival Bailey - An American in Paris 1921-1925.

    Revue neurologique·2023
    Same author

    Pharmacological inhibition of syntenin PDZ2 domain impairs breast cancer cell activities and exosome loading with syndecan and EpCAM cargo.

    Journal of extracellular vesicles·2020
    Same author

    White matter-Maximien Parchappe and the integration of articulate language.

    Journal of the history of the neurosciences·2020
    Same author

    Updates from the 2019 American Society of Clinical Oncology and European Hematology Association annual meetings: a Canadian perspective on high-risk cytogenetics in multiple myeloma.

    Current oncology (Toronto, Ont.)·2019
    Same author

    Evaluation of multi-frequency bioelectrical impedance analysis for the assessment of body composition in individuals with obesity.

    Obesity science & practice·2019

    Area of Science:

    • Physiology
    • Biophysics
    • Fluid Dynamics

    Background:

    • Current understanding of expiratory airflow limitation in mammalian airways relies on wave-speed theory.
    • A key limitation of wave-speed theory is the absence of an energy dissipation mechanism when effort exceeds maximal flow requirements.

    Purpose of the Study:

    • To investigate the relationship between expiratory airflow limitation and airway wall oscillation.
    • To identify a potential mechanism for energy dissipation during flow limitation.

    Main Methods:

    • Observation of substantial wall motion in a physical model of a trachea during flow limitation.
    • Examination of a two-dimensional mathematical model simulating tracheal behavior.
    • Comparison of model predictions with wave-speed theory.

    Related Experiment Videos

    Main Results:

    • The mathematical model aligns with wave-speed predictions for long waves.
    • The model predicts aerodynamic flutter in the supercritical flow zone.
    • Aerodynamic flutter offers a mechanism for energy dissipation and explains observed pure tones.

    Conclusions:

    • Aerodynamic flutter in supercritical flow is a plausible mechanism for energy dissipation during airway flow limitation.
    • This mechanism reconciles wave-speed theory with observed phenomena like pure tone generation.