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Assessment of Normal Pancreatic Stiffness Using 3T Magnetic Resonance Elastography
L Karakaş1, S Poçan2, A Y Karkaş3
1Department of Radiology, İstanbul Gaziosmanpaşa Training and Research Hospital, Istanbul, Turkey.
Nigerian Journal of Clinical Practice
|June 25, 2025
Summary
This study establishes normal pancreatic stiffness values using 3T magnetic resonance elastography (MRE). Pancreatic stiffness did not significantly correlate with age, sex, BMI, or pancreatic diameter in adults.
Area of Science:
- Medical Imaging
- Gastroenterology
- Biophysics
Background:
- Establishing normal pancreatic stiffness is crucial for diagnosing pancreatic diseases.
- 3T magnetic resonance elastography (MRE) is a promising technique for non-invasively assessing tissue stiffness.
Purpose of the Study:
- To determine the normal range of pancreatic stiffness in adults using 3T MRE.
- To investigate the influence of age, sex, BMI, and pancreatic dimensions on pancreatic stiffness.
Main Methods:
- Collected demographic data (age, sex, BMI) and medical history from 54 adult patients.
- Extracted MRI and MRE parameters from the hospital database.
- Measured pancreatic stiffness using 3T MRE and analyzed correlations with patient characteristics.
Main Results:
- The mean pancreatic stiffness was 1587.09 ± 114.90 Pascals.
- No significant correlations were found between pancreatic stiffness and age, sex, BMI, or pancreatic diameters (CC and AP).
Conclusions:
- This study provides essential baseline values for normal pancreatic stiffness (1587.09 ± 114.90 Pa) measured by 3T MRE.
- Demographic and anatomical factors minimally impact pancreatic stiffness, supporting MRE's utility in pancreatic disease evaluation.
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