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Updated: Sep 18, 2025

A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection
Published on: October 5, 2015
Dust to Disease: Cavitary Lung Lesion With Mycobacterium kansasii in a Black Lung Patient
Naga Vamsi Krishna Machineni1, Dedeepya Gullapalli1, Shivendra Tangutoori1
1Appalachian Regional Healthcare, Harlan, KY, USA.
Abstract:
Mycobacterium kansasii is a slow-growing mycobacterium commonly affecting the lungs, usually in a structurally deformed lung. We discuss a case of 67-year-old male with a medical history of complicated coal workers pneumoconiosis or coal mine dust lung disease presented to the pulmonary clinic with worsening dyspnea and hemoptysis with imaging findings revealing cavitary lung lesions in the right upper lobe and progressive massive fibrosis (PMF) bilaterally. Patient sputum gram stain showed acid-fast bacilli, and the cultures grew M. kansasii. He was started on rifampin, ethambutol, and azithromycin. This case highlights the importance of thorough workup of cavitary lung lesion, reinforcing the association of mycobacterium species in a patient with PMF and associated cavities.
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