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Flexible Field-Effect Transistor Sensors for Next-Generation Health Monitoring: Materials to Advanced Applications
Yaxin Li1, Huige Hu2, Jian Shu1
1Hunan Institute of Advanced Sensing and Information Technology, Xiangtan University, Xiangtan, 411105, China.
Small (Weinheim an Der Bergstrasse, Germany)
|June 25, 2025
Summary
Flexible field-effect transistor (FET) sensors offer advanced human health monitoring with multi-parametric detection and signal amplification. This review details their design, materials, and applications in wearable and implantable biosensing systems.
Area of Science:
- Materials Science
- Biomedical Engineering
- Electronics Engineering
Background:
- Flexible field-effect transistor (FET) sensors are advancing human health monitoring.
- Breakthroughs in materials, device design, and fabrication are key drivers.
- Their advantages include multi-parametric detection, signal amplification, low power, and scalability.
Purpose of the Study:
- To review the structural design and operational principles of flexible FET sensors.
- To summarize material innovations for substrates, dielectrics, channels, and electrodes.
- To analyze mechanical robustness and applications in biosensing.
Main Methods:
- Systematic review of structural design and operational principles.
- Summary of material innovations for FET components.
- Analysis of mechanical stability evaluation and optimization strategies.
- Highlighting applications in physiological monitoring and fluid analysis.
Main Results:
- Flexible FET sensors demonstrate potential for wearable and implantable biosensing.
- Material innovations enhance electrical performance and mechanical robustness.
- Strategies for improving mechanical stability under strain are analyzed.
- Successful applications in real-time physiological signal monitoring and biological fluid analysis are presented.
Conclusions:
- Flexible FET sensors are at the forefront of biosensing technologies.
- Overcoming mechanical stability challenges is crucial for practical deployment.
- Future opportunities lie in personalized health, diagnostics, and medical technologies.

