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Updated: Sep 18, 2025

Software-Assisted Quantitative Measurement of Osteoarthritic Subchondral Bone Thickness
Published on: March 18, 2022
Clinical reliability of 6 meniscal tests: a diagnostic accuracy study of 255 patients
Giuseppe Rinonapoli1, Lorenzo Lucchetta2, Giulio Ancillai1
1Orthopedics and Traumatology Department, University of Perugia, S. Maria della Misericordia Hospital, Perugia, Italy.
Abstract:
Background and purpose - We aimed to evaluate the diagnostic accuracy of 6 clinical tests for meniscal tears comparing them with MRI and arthroscopy in a cross-sectional study.
Methods:
255 patients (20-45 years) with knee trauma were examined by 2 orthopedic surgeons blinded to the patient's history, MRI result, and the first clinical examination. The clinical tests (Joint Line Tenderness, McMurray, Apley, Thessaly, Ege, and Hyper-flexion) were conducted between 5 and 7 days post-injury (T1) and 4-5 weeks post-injury (T2). Diagnostic accuracy was determined based on MRI and arthroscopic findings, evaluating sensitivity, specificity, and predictive values.
Results:
Arthroscopy confirmed 188 meniscal tears. The McMurray demonstrated the most balanced performance, with sensitivity of 91% at T1 to 80% at T2 with specificity increase from 55% to 79% showing the highest positive predictive value (PPV) of 92% at T2. Combining McMurray and Apley yielded the best accuracy minimizing false positive. McMurray and Hyper-flexion were more sensitive to medial chondropathy; Thessaly, Ege, and Hyper-flexion were more influenced by anterior knee pain.
Conclusion:
No single clinical test was sufficiently reliable for independent diagnosis, reinforcing the need for MRI confirmation and further refinement of clinical evaluation strategies.
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