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Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
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From CBCT to MR-Linac in Image-Guided Prostate Cancer Radiotherapy Towards Treatment Personalization
Florentina Larisa Coc1,2, Loredana G Marcu3,4
1Faculty of Physics, West University of Timisoara, 300223 Timisoara, Romania.
Current Oncology (Toronto, Ont.)
|June 25, 2025
Summary
Image-guided radiotherapy (IGRT) enhances prostate cancer treatment accuracy by optimizing radiation techniques and image guidance frequency. This improves target coverage and spares organs at risk, leading to better clinical outcomes.
Area of Science:
- Radiation Oncology
- Medical Physics
Background:
- Image-guided radiotherapy (IGRT) is crucial for precise prostate cancer treatment.
- IGRT offers significant advantages in dose delivery accuracy.
Purpose of the Study:
- To review factors influencing treatment accuracy in prostate cancer radiotherapy using IGRT.
- To explore radiotherapy techniques, IGRT types/frequency, and their impact on dosimetry and outcomes.
Main Methods:
- Systematic literature search of Pubmed/Medline databases.
- Analysis of 79 selected articles from an initial 152 relevant studies.
Main Results:
- Treatment regimen, radiation technique, and image guidance frequency optimize personalized treatment plans.
- Daily anatomical variations in bladder and rectum impact dosimetry; IGRT with VMAT helps spare these organs.
- IGRT enables precise dose shaping to protect critical structures.
Conclusions:
- Precise tumor targeting with IGRT reduces geometric uncertainties.
- Improved treatment outcomes include superior target coverage and enhanced organ-at-risk sparing.
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