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ISNS General Guidelines for Neonatal Bloodspot Screening 2025
Dianne Webster1, Amy Gaviglio2, Aysha Habib Khan3,4
1National Newborn Screening Laboratory, LabPlus, Health New Zealand Te Whatu Ora, Auckland 1023, New Zealand.
International Journal of Neonatal Screening
|June 25, 2025
Summary
The International Society for Neonatal Screening (ISNS) updated its 2025 guidelines for neonatal bloodspot screening. These guidelines offer a framework for developing and improving newborn screening programs globally.
Area of Science:
- Neonatal Health
- Public Health Policy
Background:
- Newborn screening (NBS) is crucial for early detection of congenital disorders.
- Existing guidelines require updates to reflect advancements in neonatal screening methodologies.
Framework:
- The 2025 ISNS General Guidelines for Neonatal Bloodspot Screening provide a comprehensive framework.
- These guidelines cover all essential aspects of a newborn screening system.
- They serve as a foundational tool for establishing, expanding, or refining NBS programs.
Implementation:
- The guidelines offer a checklist for evaluating and enhancing essential elements of screening programs.
- They are designed to assist both new and established programs in developing specific policies.
- Focus is placed on bloodspot screening for various congenital conditions.
Implications:
- These guidelines aim to enhance the quality of neonatal screening and medical services worldwide.
- They promote the dissemination of best practices in newborn screening.
- The document encourages interactive discussion for continuous improvement of neonatal screening protocols.
