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Procedure for Fabricating Biofunctional Nanofibers
Published on: September 10, 2012
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Preparation Methods and Multifunctional Applications of Functionalized Electrospun Nanofibers for Biomedicine
Jingwen Liu1, Kai Wang1, Fengying Jin1
1The First School of Clinical Medicine, Southern Medical University, Guangzhou 510515, China.
Nanomaterials (Basel, Switzerland)
|June 25, 2025
Summary
Electrospinning fabricates functionalized electrospun nanofibers (FENFs) with unique properties for biomedical uses. This review covers FENF fabrication, applications in healing and monitoring, and future research directions.
Area of Science:
- Biomaterials Science
- Nanotechnology
- Materials Engineering
Background:
- Electrospinning is a cost-effective method for creating nanofibers.
- Nanofibers offer high surface area, tunable morphology, and mechanical strength.
- These properties make them suitable for advanced biomedical applications.
Purpose of the Study:
- To review electrospinning parameters and functionalized electrospun nanofiber (FENF) fabrication.
- To explore the diverse applications of FENFs in biomedicine.
- To identify current limitations and future research avenues for FENFs.
Main Methods:
- Summarizing electrospinning process parameters.
- Detailing one-step and post-fabrication functionalization methods for FENFs.
- Compiling existing research on FENF applications and performance.
Main Results:
- FENFs exhibit antibacterial, anti-inflammatory, and tissue regenerative effects.
- FENFs show potential in drug delivery systems and biosensors.
- Applications span wound healing, cancer therapy, and health monitoring.
Conclusions:
- FENFs are versatile materials with significant biomedical potential.
- Further research can overcome current limitations and expand FENF applications.
- This review offers insights for advancing nanofiber-based material research and implementation.
