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Serological Vulnerability and Active Infection Detection Among Recently Arrived Migrants in Spain: Results from a
Guillermo Lens-Perol1, Olalla Vázquez-Cancela1,2, Magdalena Santana-Armas1
1Department of Preventive Medicine and Public Health, University Hospital of Santiago de Compostela, Rua da Choupana s/n, 15705 Santiago de Compostela, Spain.
Tropical Medicine and Infectious Disease
|June 25, 2025
Summary
Newly arrived migrants show significant gaps in vaccine-preventable disease immunity and undiagnosed infections. A one-stop health intervention effectively screened and vaccinated this population, improving public health outcomes.
Area of Science:
- Public Health
- Infectious Diseases
- Migrant Health
Background:
- Newly arrived migrants face elevated risks for communicable diseases due to low immunization coverage and limited healthcare access.
- Challenging migration trajectories further exacerbate health vulnerabilities in this population.
- This study addresses the need for targeted public health interventions for recently arrived migrants.
Purpose of the Study:
- To describe the implementation and outcomes of a novel one-stop public health intervention.
- To assess serological screening and accelerated vaccination strategies in recently arrived migrants.
- To identify immunization gaps and detect active infections within this vulnerable group.
Main Methods:
- A cross-sectional descriptive study was conducted with 335 adult migrants from sub-Saharan Africa in Galicia, Spain.
- A mobile health unit offered point-of-care screening for vaccine-preventable diseases (measles, mumps, rubella, varicella, hepatitis A) and active infections (hepatitis B, syphilis).
- An accelerated immunization schedule was provided, alongside data collection on sociodemographic and clinical factors.
Main Results:
- A high participation rate (99.7%) was achieved.
- Significant susceptibility to vaccine-preventable diseases was observed, notably hepatitis B (36.4%), measles (22.7%), and varicella (16.4%).
- Active infections were detected in 12.9% of participants, including hepatitis B (9.9%) and syphilis (3.0%).
Conclusions:
- Substantial immunization deficits and undiagnosed infections exist in vulnerable migrant populations.
- Centralized, culturally adapted screening and accelerated vaccination programs are feasible and effective.
- Integration into national health systems is recommended to ensure health equity and reduce disease transmission.
Keywords:
accelerated immunizationinfectious disease screeningmigrant healthpublic health interventionseroprevalencevaccine-preventable diseases
