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Febrile Ulceronecrotic Mucha-Habermann Disease in a 22-Month-Old Boy: A Case Presentation and Literature Review
Daniela Milanova-Ilieva1, Georgi Bukov1,2, Ksenia Baadji3
1Department of Pediatrics, St. George's University Hospital, Plovdiv, Bulgaria.
Abstract:
We report a 22-month-old boy with febrile ulceronecrotic Mucha-Habermann disease who presented with rapid progression of necrotic skin lesions and fever. The diagnosis was confirmed by histopathology, which revealed interface dermatitis, intraepidermal vesiculation, and erythrocyte extravasation. Immunohistochemistry revealed perivascular T-cell infiltration. Treatment with systemic corticosteroids, antibiotics, and antivirals achieved resolution. This case highlights diagnostic challenges and emphasizes the importance of integrating histopathology, immunohistochemistry, and prompt multimodal therapy.
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