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Updated: Sep 18, 2025

Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles
Published on: January 26, 2024
Ideal cardiovascular health status and preeclampsia: a cohort study
João Joadson Duarte Teixeira1, Bárbara Brandão Lopes1, Maria das Graças da Silva Guerreiro2
1Universidade Federal do Ceará. Fortaleza, Ceará, Brazil.
Objectives:
to evaluate the association between preeclampsia and the cardiovascular health status of pregnant women.
Methods:
we conducted a cohort study with 101 pregnant women, following ethical principles and approved by a research ethics committee. We assessed the ideal cardiovascular health using three behaviors (smoking abstinence, body mass index, and physical activity) and three factors (cholesterol, blood pressure, and absence of diabetes and cardiovascular disease). The outcome measured was preeclampsia.
Results:
preeclampsia developed in 24.75% of participants, while 9.90% had ideal cardiovascular health. We identified an association between body mass index (p < 0.01) and blood pressure (p < 0.01) with preeclampsia. However, we found no significant association between preeclampsia and overall ideal cardiovascular health status (p > 0.05).
Conclusions:
this study highlights the importance of promoting lifestyle changes in this population.
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