Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Development of Antibiotic Resistance01:30

Development of Antibiotic Resistance

232
Antibiotic resistance is a major public health concern that arises when bacteria evolve mechanisms to withstand the effects of antibiotic treatments. This resistance can be intrinsic, acquired through genetic mutations, or transferred between bacteria via horizontal gene transfer. The development of antibiotic resistance poses significant challenges in treating bacterial infections and necessitates ongoing research to develop new therapeutic strategies.Intrinsic resistance occurs when bacterial...
232
Antibiotic Selection00:57

Antibiotic Selection

55.4K
Overview
55.4K
Defense Against Bacterial Pathogens01:31

Defense Against Bacterial Pathogens

1.5K
The human immune system is a complex network of cells, tissues, and organs that work together to defend the body against bacterial infections. It consists of various immune cells, each playing a specific role in the defense mechanism.
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
1.5K
Gene Regulation in Microbial Communities: Quorum Sensing01:28

Gene Regulation in Microbial Communities: Quorum Sensing

97
Quorum sensing is a mechanism of bacterial communication that enables coordinated gene expression in response to changes in population density. This facilitates collective behaviors that enhance survival, resource acquisition, and ecological adaptation. This process relies on small signaling molecules called autoinducers that accumulate as bacterial populations grow. When a critical threshold concentration of autoinducers is reached, bacterial cells collectively modify gene expression,...
97
Environmental Applications of Microorganisms01:30

Environmental Applications of Microorganisms

295
Microorganisms play a pivotal role in maintaining ecosystem balance by recycling essential elements such as carbon, nitrogen, and phosphorus, as well as supporting processes like bioremediation, wastewater treatment, and biofuel production.Microbes in Elemental CyclesIn the carbon cycle, microorganisms decompose organic matter, releasing carbon dioxide via aerobic respiration. This carbon dioxide is subsequently used by photosynthetic organisms to synthesize organic compounds, closing the...
295
Bioremediation00:46

Bioremediation

20.3K
Bioremediation is the use of prokaryotes, fungi, or plants to remove pollutants from the environment. This process has been used to remove harmful toxins in groundwater as a byproduct of agricultural run-off and also to clean up oil spills.
20.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Marked variations in the effectiveness of commercial disinfectants against clinically relevant antibiotic-resistant bacteria and fungi.

Arhiv za higijenu rada i toksikologiju·2026
Same authorSame journal

Colonisation potential of microplastic particles containing organic pollutants by a river-isolated environmental <i>Acinetobacter baumannii</i>.

Arhiv za higijenu rada i toksikologiju·2026
Same author

Caddisfly Silk-Polycaprolactone Foams: Physicochemical and Biological Properties of Nature-Inspired Biomaterials.

Journal of functional biomaterials·2025
Same author

Molecular characterization and survival of extended-spectrum β-lactamase-producing clinical strains of Klebsiella pneumoniae isolated in Mostar, Bosnia and Herzegovina.

The new microbiologica·2025
Same author

Advances in the Applications of Clinoptilolite-Rich Tuffs.

Materials (Basel, Switzerland)·2024
Same author

Antibacterial activity of silver doped hydroxyapatite toward multidrug-resistant clinical isolates of Acinetobacter baumannii.

Journal of hazardous materials·2023

Related Experiment Video

Updated: Sep 18, 2025

Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes
08:58

Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes

Published on: March 3, 2023

6.8K

Carbapenem-resistant bacteria in the environment.

Blanka Dadić1, Jasna Hrenović1, Tomislav Ivanković1

  • 1University of Zagreb Faculty of Science, Department of Biology, Zagreb, Croatia.

Arhiv Za Higijenu Rada I Toksikologiju
|June 25, 2025
PubMed
Summary

Carbapenem-resistant bacteria (CRB) are a global health threat, found in both hospital and natural environments. Understanding their environmental reservoirs and transmission is key to controlling their spread.

Keywords:
One Health approachantibioticiantibioticsbolnički okolišhospital environmentkoncept jednog zdravljanatural environmentprirodni okolišresistancerezistencija

More Related Videos

Author Spotlight: Understanding and Detecting Environmental Antimicrobial Resistance by Combining Culture-Based Techniques and Genomics
06:54

Author Spotlight: Understanding and Detecting Environmental Antimicrobial Resistance by Combining Culture-Based Techniques and Genomics

Published on: July 19, 2024

1.2K
Antimicrobial Synergy Testing by the Inkjet Printer-assisted Automated Checkerboard Array and the Manual Time-kill Method
12:03

Antimicrobial Synergy Testing by the Inkjet Printer-assisted Automated Checkerboard Array and the Manual Time-kill Method

Published on: April 18, 2019

26.5K

Related Experiment Videos

Last Updated: Sep 18, 2025

Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes
08:58

Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes

Published on: March 3, 2023

6.8K
Author Spotlight: Understanding and Detecting Environmental Antimicrobial Resistance by Combining Culture-Based Techniques and Genomics
06:54

Author Spotlight: Understanding and Detecting Environmental Antimicrobial Resistance by Combining Culture-Based Techniques and Genomics

Published on: July 19, 2024

1.2K
Antimicrobial Synergy Testing by the Inkjet Printer-assisted Automated Checkerboard Array and the Manual Time-kill Method
12:03

Antimicrobial Synergy Testing by the Inkjet Printer-assisted Automated Checkerboard Array and the Manual Time-kill Method

Published on: April 18, 2019

26.5K

Area of Science:

  • Environmental microbiology
  • Public health
  • Antimicrobial resistance

Background:

  • Carbapenem-resistant bacteria (CRB) represent a critical public health concern due to resistance to last-resort antibiotics.
  • While extensively studied in clinical settings, their presence and dissemination pathways in environmental compartments remain less understood.
  • This knowledge gap raises significant concerns regarding potential reservoirs and transmission routes.

Purpose of the Study:

  • To review current knowledge on the occurrence, isolation, and characterization of CRB in hospital and natural environments.
  • To highlight the clinical relevance and identify environmental reservoirs of CRB.
  • To discuss the implications of CRB in the context of the One Health approach.

Main Methods:

  • Narrative review of existing literature on CRB in environmental settings.
  • Identification of common CRB species pathogenic to humans, including *Acinetobacter baumannii*, *Klebsiella pneumoniae*, and *Pseudomonas aeruginosa*.
  • Summary of isolation and characterization methods, including selective media, phenotypic assays, and molecular tools.

Main Results:

  • CRB are frequently detected in diverse environments such as sewage, wastewater treatment plants, water bodies, sediments, soil, animals, and plants.
  • Anthropogenic factors, particularly effluent discharge from wastewater treatment plants, are major contributors to CRB presence in the environment.
  • Key CRB species like *A. baumannii*, *K. pneumoniae*, and *P. aeruginosa* are prevalent in these environmental compartments.

Conclusions:

  • CRB are widespread in both clinical and environmental settings, underscoring the need for integrated management strategies.
  • The One Health approach is essential for understanding and mitigating CRB transmission across human, animal, and environmental interfaces.
  • Further research into strain-level dissemination patterns and environmental persistence mechanisms is crucial for developing effective control measures.