Related Experiment Video
Updated: Sep 18, 2025

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression
Published on: April 26, 2024
Insomnia Subtypes in Clinical Population According to the Insomnia Type Questionnaire (ITQ): A Multi-Centre Study in
Francesca Canellas1, Manuel de Entrambasaguas2, Odile Romero3
1Hospital Universitari Son Espases, Health Research Institute of the Balearic Islands (IdISBa), Institut Universitari D'investigacions en Ciències de la Salut (IUNICS) Universitat de les Illes Balears, Palma, Spain.
Abstract:
The lack of robust subtyping for insomnia disorder (ID) led to its current classification as a uniform condition. A novel approach to subtyping ID developed a new tool, the insomnia type questionnaire (ITQ). Our research aimed to assess whether the ID subtypes identified in the general population could also be found in ID patients referred to sleep clinics in a multi-centre study throughout Spain, and to gather insights for the management of complex ID patients. The ITQ classified ID patients into the five previously described subtypes: Type 1 = 35.1%, Type 2 = 12%, Type 3 = 46.7%, Type 4 = 5.8% and Type 5 = 0.4%. Compared to the general population, there was an overrepresentation of Types 1 and 3, consistently across all participating clinical centres. The total self-reported sleep duration was 4.7 (SD 1.2) h, with no significant differences between subtypes. Type 1 patients had significantly higher scores in the Insomnia Severity Index, Inventory of Depressive Symptomatology self-rated and State-Trait Anxiety Inventory. Type 3 patients were more worried about their sleep. Type 4 had the lowest depression and anxiety scores. ITQ subtyping showed that ID patients attending sleep clinics had high scores in depression, specially Type 1 patients, who probably need a differentiated therapeutic approach. The over-representation of Type 3 patients suggests that they are more worried about their sleep than the other subtypes. These findings highlight the difficulties faced by sleep clinicians to treat complex and refractory-toto-treatment ID patients and those with comorbid insomnia.
Related Concept Videos
Insomnia
Multiple factors contribute...
Management of Insomnia
Substance Use Disorders Affecting Sleep
Understanding the concepts of physical dependence,...
Sedatives and Hypnotics Drugs: Miscellaneous Agents
Melatonin congeners like ramelteon (Rozerem) and tasimelteon (Hetlioz) selectively bind to melatonin receptors (MT1 and MT2) and thus mimic the actions of melatonin, a hormone that regulates sleep-wake cycles. Tasimelteon is primarily used for non-24-hour sleep-wake disorder, common in blind patients. They are also used to treat conditions like insomnia...
Narcolepsy
Sleep-Wake Cycles
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:

