Related Experiment Video
Updated: Sep 18, 2025
04:21
CRISPR-Cas9 Mediated Gene Deletion in Human Pluripotent Stem Cells Cultured Under Feeder-Free Conditions
Published on: November 1, 2024
828
Virus-induced gene editing free from tissue culture
Abraham R Steinberger1,2, Daniel F Voytas3,4
1Department of Plant and Microbial Biology, University of Minnesota, St. Paul, MN, USA.
Nature Plants
|June 25, 2025
Summary
Virus-induced gene editing (VIGE) is now a viable standalone plant gene editing method, moving beyond traditional transgenesis. Recent innovations highlight VIGE
Area of Science:
- Plant biotechnology and genome engineering.
Background:
- Virus-induced gene editing (VIGE) was initially conceived as an alternative to traditional plant gene editing techniques.
- Historically, VIGE relied on tissue-culture-mediated transgenesis, undermining its independence.
- Recent technological advancements have established VIGE as a distinct and viable gene editing strategy.
Purpose of the Study:
- To discuss the potential advances in plant genome engineering enabled by VIGE.
- To review the progress made in VIGE technology.
- To identify the ongoing challenges hindering VIGE's full potential.
Main Methods:
- Discussion of recent innovations in VIGE.
- Analysis of progress in VIGE applications.
- Identification of challenges in VIGE implementation.
Main Results:
- VIGE has overcome its historical reliance on transgenesis.
- VIGE is emerging as an independent and effective plant gene editing technology.
- Significant progress has been made, but challenges remain for VIGE.
Conclusions:
- VIGE represents a significant advancement in plant genome engineering.
- Further research and development are needed to overcome existing challenges.
- VIGE holds promise for unlocking new possibilities in crop improvement and biotechnology.
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