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Ezocgabine or retigabine, an antiepileptic drug of remarkable efficacy, has revolutionized the management of seizures. It is a potassium channel activator, explicitly targeting the family of Q subtype potassium channels. It enhances the transmembrane potassium currents, regulating neuronal excitability. This action stabilizes the resting membrane potential, a pivotal factor in mitigating the hyperexcitability that characterizes epilepsy.
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Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early...
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Related Experiment Video

Updated: Sep 18, 2025

Implementation of Portable Emissions Measurement Systems PEMS for the Real-driving Emissions RDE Regulation in Europe
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EUPC Implementation in Greece.

Ioulia Bafi1, Eftychia Georgoulopoulou2, Maria Kyriakidou3

  • 1Greek Monitoring Centre for Drugs, Alcohol and Addictive Behaviours/EUDA's Greek Focal Point, University Mental Health, Neurosciences & Precision Medicine Research Institute 'Costas Stefanis' (UMHRI), 2 Soranou Tou Efesiou, 11527, Athens, Greece. ibafi@ektepn.gr.

Journal of Prevention (2022)
|June 25, 2025
PubMed
Summary

The European Prevention Curriculum (EUPC) training in Greece has equipped 89 professionals since 2019 with evidence-based prevention practices. This initiative fosters a common language and systematic approaches for effective prevention strategies.

Keywords:
Drug preventionEUPCPreventionProfessional training

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Area of Science:

  • Public Health
  • Health Policy
  • Substance Abuse Prevention

Background:

  • The European Prevention Curriculum (EUPC) was implemented in Greece via the ASAP training project.
  • Comprehensive EUPC training, including basic and advanced modules, was developed for policymakers.

Purpose of the Study:

  • To assess the impact and reach of the European Prevention Curriculum (EUPC) training in Greece.
  • To evaluate the effectiveness of EUPC in establishing a common prevention language and promoting evidence-based practices.

Main Methods:

  • Training delivery by four accredited trainers using an updated Trainer's Guide.
  • Engagement of 89 professionals in EUPC training between 2019 and mid-2024.
  • Minor adaptations to training duration to enhance stakeholder engagement and reflection.

Main Results:

  • EUPC training established a common language in prevention and updated professionals with current evidence-based practices.
  • The curriculum empowered professionals, emphasizing rigorous, systematic approaches to prevention.
  • Challenges included resistance to change and the need for structured evaluations.

Conclusions:

  • EUPC has successfully contributed to enhancing prevention strategies and interventions in Greece.
  • Future plans include expanding EUPC into the education sector and to regional/local levels.
  • Sustainability and broader risk behavior focus are key future objectives for EUPC.