Widening of inter-Purkinje cell distances in association with corpora amylacea

Inter-Purkinje cell distances were determined in random routine cerebellums obtained at autopsies of adults over the age of 50. There was a significant increase in the inter-Purkinje cell distances proportionate to the increase in adjacent corpora amylacea. The possibility of replacement of Purkinje cells by corpora amylacea is discussed.